Rapid screening detection of fluoroquinolone residues in milk based on turn-on fluorescence of terbium coordination polymer nanosheets  

作　　者：Xin Xu Lixia Feng Jie Li Ping Yuan Jiangao Feng Lijun Wei Xianglei Cheng 

机构地区：[1]Jiangxi Province Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University

出　　处：《Chinese Chemical Letters》2019年第3期549-552,共4页中国化学快报（英文版）

基　　金：financial supports from the National Natural Science Foundation of China (Nos.81760601, 21265013 and 81260435);the Natural Science Foundation of Jiangxi Province(No.20171BAB215050);the Innovation Fund Designated for Graduate Students of Jiangxi Province(No.YC2017S085)

摘　　要：We report a facile, effective and rapid screening method for the determination of total fluoroquinolones(FQs) in milk using lanthanide coordination polymer nanomaterials as the sensing platform. The nonluminescent coordination polymer nanosheets(CPNSs) used in this work are composed of adenosine monophosphate(AMP) and terbium(Tb^(3+)) ions(AMP/Tb CPNSs). The as-prepared CPNSs were characterized by transmission electron microscopy, Fourier transform infrared spectroscopy and fluorescence techniques. Tb^(3+) acts as the center ion of the coordination polymer, with AMP assembled through phosphate and amine groups. However, the reaction between FQs and AMP/Tb CPNSs noticeably turns on the fluorescence due to the strong coordination interaction between FQs and Tb^(3+). Under optimized conditions, the fluorescence intensity of AMP/Tb at 545 nm shows a linear relationship with FQ concentrations between 0.04 μmol/L and 5.0 μmol/L. The relative standard deviation(RSD) of the intraday precision is below 1%, and detection limits are as low as 0.01 μmol/L. The proposed method was successfully applied to the determination of FQs in milk samples.We report a facile, effective and rapid screening method for the determination of total fluoroquinolones(FQs) in milk using lanthanide coordination polymer nanomaterials as the sensing platform. The nonluminescent coordination polymer nanosheets(CPNSs) used in this work are composed of adenosine monophosphate(AMP) and terbium(Tb^(3+)) ions(AMP/Tb CPNSs). The as-prepared CPNSs were characterized by transmission electron microscopy, Fourier transform infrared spectroscopy and fluorescence techniques. Tb^(3+) acts as the center ion of the coordination polymer, with AMP assembled through phosphate and amine groups. However, the reaction between FQs and AMP/Tb CPNSs noticeably turns on the fluorescence due to the strong coordination interaction between FQs and Tb^(3+). Under optimized conditions, the fluorescence intensity of AMP/Tb at 545 nm shows a linear relationship with FQ concentrations between 0.04 μmol/L and 5.0 μmol/L. The relative standard deviation(RSD) of the intraday precision is below 1%, and detection limits are as low as 0.01 μmol/L. The proposed method was successfully applied to the determination of FQs in milk samples.

关 键 词：Fluoroqui no lones TERBIUM coordination polymer NANOSHEETS FLUORESCENCE Screening DETECTION 

分 类 号：O6[理学—化学]