大腔导管抽吸联合导管溶栓与单纯导管溶栓在急性下肢深静脉血栓形成治疗中的疗效比较  

Outcomes of Large Cavity Catheter Aspiration Combined with Catheter Directed Thrombolysis vs Pure Catheter Directed Thrombolysis in Treatment of Acute Deep Venous Thrombosis in Lower Extremity

作　　者：李荣宾[1] 陈卢锋 蔡旭东[1] LI Rongbin;CHEN Lufeng;CAI Xudong(Department of Vascular Surgery,The Second Affiliated Hospital of Fujian Medical University,Quanzhou 362000,China)

机构地区：[1]福建医科大学附属第二医院血管外科

出　　处：《福建医科大学学报》2019年第2期98-101,共4页Journal of Fujian Medical University

基　　金：泉州市科技局重点项目(2014Z25)

摘　　要：目的分析比较大腔导管血栓抽吸联合导管溶栓和单纯导管溶栓在治疗急性下肢深静脉血栓(DVT)中的疗效差别。方法收集急性DVT患者62例,分2组,其中实验组29例,行大腔导管血栓抽吸后导管接触性溶栓;对照组33例,单纯行导管接触性溶栓。对比2组的患肢消肿率、溶栓效果、溶栓时间、溶栓药用量、出血并发症和2年通畅率、血栓形成后综合征(PTS)发生率情况。结果实验组在患肢消肿率、溶栓效果、溶栓时间、溶栓药用量和2年通畅率方面均优于对照组,而在出血并发症及PTS发生率方面低于对照组。结论大腔导管吸栓联合导管接触性溶栓对急性DVT的治疗安全有效,有一定的临床应用价值。Objective To compare the clinical efficacies of large cavity catheter aspiration combined with catheter directed thrombolysis (CDT) and pure CDT for acute lower extremity deep venous thrombosis (DVT).MethodsSixty two cases of acute DVT of lower extremity were analyzed retrospectively.Of all patients,29 cases(observation group)were treated with large cavity catheter aspiration combined with CDT,33 cases (control group)were treated with pure CDT.Limb swelling remission rate, thrombolysis effect, time, dosage, complication rate, deep vein patency, and the incidence of post-thrombotic syndrome(PTS)after 2 years were evaluated between two groups.ResultsCompared with the control group, the thrombolysis effect, time, dosage, limb swelling remission rate, and deep vein patency after 2 years were significantly better in the observation group.The rate of complication and PTS in the observation group were lower than that of observation group.ConclusionTreatment of acute DVT with large cavity catheter aspiration combined with CDT is safe, effective and has certain clinical application value.

关 键 词：静脉血栓形成 导管 留置 血栓溶解疗法 栓塞 治疗性 治疗效果 

分 类 号：R323.72[医药卫生—人体解剖和组织胚胎学] R45[医药卫生—基础医学]