蜂毒清2号联合血液净化治疗对重度蜂蜇伤患者心、肝、肾影响的临床研究  

Clinical Study on the Effect of Fengduqing 2 Combined with Blood Purification Therapy on Heart,Liver and Kidney of Severe Bee sting Patients

作　　者：潘文[1] 屈阳 米俊[1] 赵强[1] 武琪[1] 郭修贵 周荣赛 朱定海 廖文俊 Pan Wen;Qu Yang;Mi Jun(Ankang Hospital of Traditional Chinese Medicine of Shaanxi Province,Shaanxi,Ankang 725000,China)

机构地区：[1]陕西省安康市中医医院,陕西安康725000

出　　处：《中国中医急症》2019年第5期837-840,共4页Journal of Emergency in Traditional Chinese Medicine

基　　金：陕西省安康市科技局科研项目(2016AK-03-07)

摘　　要：目的观察自拟中药(蜂毒清颗粒2号)对重度毒蜂蜇伤患者的临床疗效。方法患者40例随机分为两组,对照组给予常规治疗方案加血液灌流治疗,治疗组在对照组基础上予蜂毒清2号颗粒口服,复查对比其肝功、肾功、心肌酶、血乳酸等相关指标,比较两组急性生理与慢性健康(APACHEⅡ)评分。结果治疗组总有效率为90.00%,显著高于对照组的80.00%(P <0.05)。两组治疗后心肌酶、肝功、肾功、乳酸指标均较治疗前显著下降(P <0.05),治疗组下降更为显著(P <0.05)。治疗后两组APACHEⅡ评分均较治疗前显著下降(P <0.05),治疗组较对照组下降更为明显(P <0.05)。治疗组与对照组患者在治疗(留观)时间上分别是10 d、14 d,差异有统计学意义(P <0.05)。结论重度蜂蜇伤患者在早期给予西医常规治疗联合血液灌流同时,口服(或鼻饲)蜂毒清2号颗粒可以减轻其病痛,更好地改善重度蜂蜇伤患者心肝肾功能,缩短病程时间,提高临床疗效。Objective: To observe the clinical effect of self-made Chinese medicine (Fengduqing Granule 2) on severe poisonous bee sting. Methods: 40 patients were randomly divided into two groups. The control group was given routine treatment plus hemoperfusion,while the treatment group was given Fenduqing 2 orally on the basis. The liver function,kidney function,myocardial enzymes,blood lactic acid and other related indicators were compared,and the acute physiology and chronic health(APACHEⅡ) scores of the two groups were compared. Results: The total effective rate was 90.00% in the treatment group,significantly higher than 80.00% in the control group(P < 0.05). After treatment,the indices of myocardial enzymes,liver function,kidney function and lactic acid in the two groups were significantly lower than those before treatment(P < 0.05),and the decrease in the treatment group was more significant(P < 0.05). After treatment,APACHE II scores dropped significantly in the two groups(P < 0.05),and the decrease of the treatment group was more obvious than that of the control group(P < 0.05). The treatment time of the treatment group and the control group were 10 days and 14 days respectively;the difference was statistically significant(P < 0.05). Conclusion: Routine Western medicine treatment combined with hemoperfusion treatment and taking Fenduqing 2 orally(or nasal feeding) can relieve patients' pain,better improve their heart,liver and kidney function,shorten the course of disease and improve the clinical efficacy in the early stage.

关 键 词：毒蜂蜇伤 蜂毒清2号 血液净化治疗 

分 类 号：R269[医药卫生—中西医结合]