中药联合规范化护理对中晚期食管癌患者疼痛并抑郁的疗效观察  

Observation on the curative effect of traditional Chinese medicine combined with standardized nursing on pain and depression in patients with advanced esophageal cancer

作　　者：韩素雅[1] 王玉强[1] 路大鹏[2] 齐增平[1] 张传杰 李绵 耿惠[1] Han Su-ya;Wang Yu-qiang;Lu Da-peng;Qi Zeng-ping;Zhang Chuan-jie;Li Mian;Geng Hui(Department of Oncology, Hebei General Hospital of Civil Affairs, Hebei Xingtai 054000;Medical Imaging Department, Hebei General Hospital of Civil Affairs, Hebei Xingtai 054000)

机构地区：[1]河北省民政总医院肿瘤内科,河北邢台054000 [2]河北省民政总医院医学影像科,河北邢台054000

出　　处：《实用临床护理学电子杂志》2019年第17期3-4,6,共3页Electronic Journal of Practical Clinical Nursing Science

基　　金：邢台市科学技术研究与发展计划项目;(编号:2018ZC087)

摘　　要：目的探讨中药联合规范化护理对中晚期食管癌患者疼痛并抑郁的临床疗效。方法将入选的86例中晚期食管癌疼痛并抑郁患者,按照住院时间随机分为对照组和观察组,每组各43例,两组患者均给予抗癌、支持治疗及常规护理,对照组根据疼痛情况按阶梯镇痛治疗,抗抑郁选用盐酸帕罗西汀片,观察组在对照组基础上给予中药联合规范化护理,治疗14天,观察两组患者疼痛评分(NRS),疼痛缓解情况,抑郁评分(SDS)和不良反应。结果两组患者治疗后疼痛和抑郁评分均低于治疗前(P<0.05),且观察组患者疼痛和抑郁评分低于对照组(P<0.05);观察组患者疼痛缓解总有效率为73.81%,高于对照组疼痛缓解总有效率的44.19%(P<0.05);观察组患者厌食、恶心、便秘、嗜睡、头晕不良反应的发生率均明显低于对照组(P<0.05)。结论中药联合规范化护理能明显改善中晚期食管癌患者的疼痛和抑郁症状,减少不良反应发生率。Objective To explore the clinical effect of traditional Chinese medicine combined with standardized nursing on pain and depression in patients with advanced esophageal cancer. Methods 86 patients with esophageal cancer pain and depression were randomly divided into control group and observation group according to hospitalization time. 43 patients in each group were given anti-cancer, supportive treatment and routine nursing. The control group was given step-by-step analgesic treatment according to the pain situation, and paroxetine hydrochloride tablets were used for anti-depression. The observation group was given standardized nursing of traditional Chinese medicine combined with traditional Chinese medicine on the basis of the control group. After 14 days of treatment, pain score (NRS), pain relief, depression score (SDS) and adverse reactions were observed. Results The pain and depression scores of the two groups after treatment were lower than those before treatment (P<0.05), and the pain and depression scores of the observation group were lower than those of the control group (P<0.05);the total effective rate of pain relief in the observation group was 73.81%, higher than that in the control group, 44.19%(P<0.05);the adverse reactions of anorexia, nausea, constipation, sleepiness and dizziness in the observation group were lower than those before treatment (P<0.05). The incidence was significantly lower than that of the control group (P <0.05). Conclusion Traditional Chinese medicine combined with standardized nursing can significantly improve the pain and depression symptoms of patients with advanced esophageal cancer, and reduce the incidence of adverse reactions.

关 键 词：食管癌 疼痛 抑郁 中药 规范化护理 疗效 

分 类 号：R473[医药卫生—护理学]