二维超声斑点追踪成像评价初诊甲状腺功能亢进患者左心室纵向收缩功能及同步性  

Assessment of Left Ventricular Longitudinal Systolic Function and Synchrony in Patients with Newly Diagnosed Hyperthyroidism by Two-dimensional Ultrasonic Speckle Tracking Imaging

作　　者：刘蓉 尹立雪[1,3] 谭静 张文军[2] 周密[2] 胥卉萍[2] LIU Rong;YIN Lixue;TAN Jing;ZHANG Wenjun;ZHOU Mi;XU Huiping(Cardiovascular Ultrasound and Non-invasive Cardiology Department, Key Laboratory of Ultrasound in Cardiac Electrophysiology and Bio-mechanics of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital,Chengdu 610072,China)

机构地区：[1]西南医科大学附属医院超声诊断教研室,四川泸州646000 [2]成都市温江区人民医院,四川成都611130 [3]四川省医学科学院、四川省人民医院心血管超声及心功能科,超声心脏电生理学与生物力学四川省重点实验室,四川成都610072

出　　处：《中国医学影像学杂志》2019年第5期339-343,共5页Chinese Journal of Medical Imaging

摘　　要：目的应用二维超声斑点追踪成像评价初诊甲状腺功能亢进(甲亢)患者左心室纵向收缩功能及其同步性,揭示初诊甲亢患者左心室功能受损情况。资料与方法选择初次诊断为甲亢的47例患者为甲亢组。选择同期健康体检人群34例为对照组。分别获取两组左心室射血分数(LVEF)及左心室各壁共18节段的收缩期纵向峰值应变及达峰时间,比较两组间的差异。结果甲亢组常规二维超声LVEF值与对照组比较,差异无统计学意义(P>0.05)。甲亢组左心室多个节段的纵向峰值应变值均明显小于对照组,差异有统计学意义(P<0.05)。甲亢组左心室所有节段纵向应变达峰时间均较对照组提前,除前间隔基底段外,其余各节段与对照组差异均有统计学意义(P<0.05)。结论在临床诊断甲亢性心脏病之前,甲亢患者已经出现收缩期左心室节段性心肌力学功能下降和运动同步性减低。Purpose To assess theleft ventricular longitudinal systolic function and synchrony in patients with newly diagnosed hyperthyroidism by two-dimensional ultrasonic speckle tracking imaging, and to reveal the impairment of left ventricular function in patients with newly diagnosed hyperthyroidism. Materials and Methods Forty-seven patients with newly diagnosed hyperthyroidism were selected as the hyperthyroidism group, and thirty-four healthy subjects over the same period were selected as the control group. The left ventricular ejection fraction (LVEF) and systolic longitudinal peak strain & peak time of 18 segments of left ventricular walls in the two groups were obtained respectively, and the differences between the two groups were compared. Results There was no statistically significant difference in the routine two-dimensional ultrasound LVEF between the hyperthyroidism group and the control group (P>0.05). In addition, the longitudinal peak strain values of multiple segments of the left ventricle in the hyperthyroidism group were significantly lower than those in the control group (P<0.05). Moreover, the peak time of longitudinal strain in all segments of the left ventricle in the hyperthyroidism group was earlier than that in the control group, and the differences in all segments (except the anterior septal basal segment) between hyperthyroidism group and control group were statistically significant (P<0.05). Conclusion Before the clinical diagnosis of hyperthyroidism heart disease, the hyperthyroidism patients present the systolic left ventricular segmental myocardial mechanical function decrease and the lowered motion synchronization.

关 键 词：甲状腺功能亢进症 超声心动描记术 斑点追踪成像 心室功能 左 

分 类 号：R581.1[医药卫生—内分泌] R445.1[医药卫生—内科学]