比索洛尔治疗慢性心功能不全合并心肌梗死效果及对舒张压和收缩压的影响  

Bisoprolol for chronic cardiac insufficiency complicated with myocardial infarction and its effect on diastolic and systolic blood pressures

作　　者：丁志文 钱进[1] 刘志伟[1] Ding Zhiwen;Qian Jin;Liu Zhiwei(Dongguan Huangjiang Hospital, Dongguan 523750,China)

机构地区：[1]东莞市黄江医院,523750

出　　处：《国际医药卫生导报》2019年第10期1609-1611,共3页International Medicine and Health Guidance News

摘　　要：目的慢性心功能不全合并心肌梗死患者应用比索洛尔治疗效果及舒张压与收缩压指标分析。方法 选取2017年12月至2018年12月本院诊治慢性心功能不全合并心肌梗死患者70例,随机分成两组,各35例。对照组予常规方案,研究组予比索洛尔方案,分析两组血压指标、心功能指标及不良反应情况。结果 治疗后,研究组舒张压、收缩压分别为(72.51±12.53)mmHg、(112.54±13.26)mmHg,均低于对照组,差异均有统计学意义(均P<0.05);治疗后,研究组心率、LVEDV、LVESV分别为(78.06±12.68)次/min、(82.56±8.74)ml、(42.58±6.85)ml,均低于对照组,LVEF(49.18±2.92)%,高于对照组,差异均有统计学意义(均P<0.05);两组患者均无严重不良反应。结论 慢性心功能不全合并心肌梗死患者应用比索洛尔治疗,能有效改善患者舒张压、收缩压指标,以及机体心功能指标,且具用药安全性。Objective To analyze the effect of bisoprolol for patients with chronic cardiac insufficiency and myocardial infarction and its influence on diastolic and systolic blood pressures. Methods Seventy patients with chronic cardiac insufficiency and myocardial infarction were enrolled in our hospital from December 2017 to December 2018.They were randomly divided into a control group and a study group. The control group were treated with routine regimen, and the study group with bisoprolol regimen. The blood pressure indicators, cardiac function indicators, and adverse reactions in both groups were analyzed. Results After the treatment, the diastolic and systolic blood pressures, heart rate, LVEDV, LVESV, and LVEF were (72.51±12.53)mmHg,(112.54±13.26) mmHg,(78.06±12.68)times/min,(82.56±8.74)ml,(42.58±6.85)ml,(49.18±2.92)% in the study group, which were better than those in the control group (all P < 0.05). No serious adverse reactions occurred in both groups. Conclusion Bisoprolol for patients with chronic cardiac insufficiency and myocardial infarction treated can effectively improve their diastolic and systolic blood pressures and cardiac function, and is safe.

关 键 词：慢性心功能不全 心肌梗死 比索洛尔 舒张压 收缩压 心功能 

分 类 号：R542.22[医药卫生—心血管疾病]