复方皂矾功能洗发香波对马拉色菌体外抑菌活性的实验研究  

Experimental Study on Antibacterial Activity of Compound Zaofan Functional Shampoos on Malassezia in Vitro

作　　者：高坤平 杨文信 GAO Kunping;YANG Wenxin(Department of Dermatology,the Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University,Sichuan Province,Luzhou 646000,China)

机构地区：[1]西南医科大学附属中医院皮肤科

出　　处：《中国中医药现代远程教育》2019年第11期111-113,共3页Chinese Medicine Modern Distance Education of China

基　　金：四川省科技计划项目【No.2014SZ0186】;四川省中医药管理局四川省中医药产业创新团队项目【No.2017C011】;西南医科大学与西南医科大学附属中医医院联合项目【No.[2013]12】

摘　　要：目的用琼脂平板扩散法(打孔法)和微量稀释法,观察复方皂矾功能洗发香波药物原液对马拉色菌的体外抑菌活性。方法稀释成不同浓度的采乐洗剂设为对照组,稀释成不同浓度的复方皂矾功能洗发香波药物原液设为实验组,用琼脂平板扩散法(打孔法)和用微量液基稀释法测试体外对马拉色菌的抑制作用,并测定复方皂矾功能洗发香波药物原液MIC(最小抑菌浓度)值。结论复方皂矾功能洗发香波药物原液在体外有抑制马拉色菌的作用。复方皂矾功能洗发香波药物原液的MIC(最小抑菌浓度)值为0.005g/mL。Objective The inhibition of malassezia in vitro was tested by two methods, perforation method and microdilution method. Methods The drug Triatop lotion diluted into different concentrations was assigned to the control group, and the compound zaofan functional shampoo drug concentrate diluted into different concentrations was assigned to the experimental group. The inhibitory effect on malassezia in vitro was tested using AGAR plate diffusion method (perforation method) and microliquid-based dilution method, and the MIC (minimum inhibitory concentration) value of the drug concentrate diluted into compound zaofan functional shampoo drug was determined. Conclusion Compound zaofan functional shampoo drug chemicals have a strong effect on malassezia. The MIC value of compound zaofan functional shampoo drug stock was 0.005g/ml.

关 键 词：复方皂矾功能洗发香波药物原液 脂溢性皮炎 马拉色菌 体外抑菌 抑菌圈直径 MIC 实验研究 

分 类 号：R285[医药卫生—中药学]