自我效能在食管癌化疗患者健康素养与生活质量间的中介效应及调节效应  

Mediating and modulating effects of self-efficacy between health literacy and quality of life in patients with esophagus cancer receiving chemotherapy

作　　者：程红萍[1] 路清蒲[1] 杨红梅[1] Cheng Hongping;Lu Qingpu;Yang Hongmei(Department of Nursing, Heping Hospital Affiliated to Changzhi Medical University, Changzhi 046000, China)

机构地区：[1]长治医学院附属和平医院护理部,长治046000

出　　处：《中华现代护理杂志》2019年第8期1004-1007,共4页Chinese Journal of Modern Nursing

摘　　要：目的分析自我效能在食管癌化疗患者健康素养与生活质量间的中介效应及调节效应。方法采用便利抽样法选取2015年1月—2017年12月于长治医学院附属和平医院行食管癌化疗的患者105例为研究对象,采用一般自我效能感量表(GSES)中文版、慢性病患者健康素养量表(HeLMS)及Spitzer生活质量指数(SQLI)对患者进行问卷调查,采用Pearson相关分析调查患者自我效能、健康素养和生活质量之间的相关性,采用回归分析研究变量间的中介效应和调节效应。结果105例患者自我效能条目均分为(2.38±0.47)分,健康素养得分为(86.65±12.29)分,生活质量得分为(4.94±0.55)分。Pearson相关分析显示,自我效能与健康素养、生活质量呈正相关(r=0.517、0.462;P<0.05)。自我效能在食管癌化疗患者健康素养与生活质量间存在一定的中介效应,中介效应占总效应比例为34.82%。回归分析显示,交互作用项"健康素养×自我效能"的回归系数有统计学意义(β'=0.015,t=2.718;P<0.01),且调节效应显著(ΔR2=0.018,P<0.01)。结论自我效能在食管癌化疗患者健康素养与生活质量间起中介效应及调节效应。Objective To analyze the mediating and modulating effects of self-efficacy between health literacy and quality of life in patients with esophagus cancer receiving chemotherapy. Methods Totally 105 patients receiving chemotherapy for esophagus cancer in Heping Hospital Affiliated to Changzhi Medical University from January 2015 to December 2017 were selected by convenient sampling and investigated with General Self Efficacy Scale (GSES), Health Literacy Management Scale (HeLMS) and Spitzer Quality of Life Index (SQLI). Pearson correlation analysis was used to analyze the correlation between the patients' self-efficacy, health literacy and quality of life, and regression analysis was used to mediating and modulating effects between the variables. Results The average self-efficacy score, health literacy score and quality of life score of the 105 patients were (2.38±0.47),(86.65±12.29) and (4.94±0.55), respectively. Pearson correlation analysis showed that self-efficacy was positively correlated with health literacy and quality of life (r=0.517, 0.462;P<0.05). Self-efficacy showed mediating effects between health literacy and quality of life in the patients with esophagus cancer, which accounted for 34.82% in the total effect. Regression analysis showed that the regression coefficient of the interacting "health literacy×self-efficacy" was statistically significant (β'=0.015, t=2.718;P<0.01), whose mediating effect was significant (ΔR2=0.018, P<0.01). Conclusions Self-efficacy has mediating and modulating effects between health literacy and quality of life in patients receiving chemotherapy for esophagus cancer.

关 键 词：食管肿瘤 生活质量 自我效能 健康素养 中介效应 调节效应 化疗 

分 类 号：R473.73[医药卫生—护理学]