中国人玫瑰痤疮患病率的Meta分析  

The prevalence of rosacea in China: a meta-analysis

作　　者：郭宏佐 张钰汇 孙艳[1] 肖碧环[1] 吴严[1] GUO Hongzuo;ZHANG Yuhui;SUN Yan;XIAO Bihuan;WU Yan(Department of Dermatology,the First Hospital of China Medical University,Shenyang,110013,P.R.China)

机构地区：[1]中国医科大学附属第一医院皮肤科,沈阳110013

出　　处：《中国循证医学杂志》2019年第5期543-549,共7页Chinese Journal of Evidence-based Medicine

摘　　要：目的系统评价中国人玫瑰痤疮的患病率。方法计算机检索PubMed、The Cochrane Library、EMbase、CNKI、WanFang Data和VIP数据库,搜集关于中国人玫瑰痤疮患病率的文献,检索时限均为建库至2018年9月5日。由2名研究者独立筛选文献和提取资料后,采用Stata 12.0软件进行Meta分析。结果共纳入54篇文献。44篇是基于人群或社区的研究,合并患病率为0.27%[95%CI(0.22,0.31)];10篇是基于医院的研究,合并患病率为1.47%[95%CI(1.08,1.86)]。基于人群或社区研究中患病率最高为80年代初期(2.19%),随后逐年下降,至90年代初期最低(0.17%),2015年回升至1.24%。而基于医院的研究患病率近10年最高,达4.64%。无论基于人群或社区还是基于医院的研究,西北和华北均有较高的患病率(基于人群或社区:西北1.24%,华北1.1%;基于医院:西北6.03%,华北2.83%),华东和华南患病率均较低(基于人群或社区:华东0.02%,华南0.32%;基于医院:华南0.28%)。基于人群或社区研究中,女性患病率(0.36%)高于男性(0.19%)。结论中国人玫瑰痤疮基于人群或社区研究的合并患病率为0.27%,基于医院研究的合并患病率为1.47%,西北和华北高发,女性患病率高于男性。Objectives To systematically review the prevalence of rosacea in China. Methods PubMed, The Cochrane Library, EMbase, CNKI, WanFang Data and VIP databases were electronically searched to collect literature of the prevalence of rosacea in China from inception to September 5 th, 2018. Two reviewers independently screened literature, extracted data and then meta-analysis was performed by using Stata 12.0 software. Results A total of 54 studies were included. The pooled prevalence of rosacea from 44 population-based or community-based studies was 0.27%(95%CI 0.22 to 0.32) and from 10 hospital-based studies was 1.47%(95%CI 1.08 to 1.86). Based on population-based or community-based studies, the highest prevalence was in the early 1980 s(2.19%), followed by a gradual decline, to the lowest(0.17%) in the early 1990 s, after that the prevalence increased to 1.24% till 2015. Based on hospital-based studies,the prevalence had a maximum of 4.64% in the past decade. The Northwest China and North China had higher prevalence of rosacea(population-based or community-based studies: 1.24% in Northwest China, 1.1% in North China;hospitalbased studies: 6.03% in Northwest China, 2.83% in North China). The prevalence in East China and South China was relatively low(population-based or community-based studies: 0.02% in East China and 0.32% in South China;Hospitalbased studies: 0.28% in South China). The prevalence of rosacea in female(0.36%) was higher than that of male(0.19%) in population-based or community-based studies. Conclusions In China, the pooled prevalence of rosacea is 0.27% in population-based or community-based studies and 1.47% in hospital-based studies. Rosacea is common in North China and Northwest China. Female has higher prevalence than male.

关 键 词：中国 玫瑰痤疮 患病率 META分析 

分 类 号：R758.734[医药卫生—皮肤病学与性病学]