急性ST段抬高型心肌梗死发病时间与住院期间恶性心律失常事件的关系研究  

Correlation between the time of ST segment elevation myocardial infarction and malignant arrhythmic events during hospitalization

作　　者：孙秀华[1] 屈百鸣[1] 金钦阳[1] 王欢[1] 张庆刚[1] SUN Xiuhua;QU Baiming;JIN Qinyang(Department of Cardiovascular Disease, Zhejiang Provincial People's Hospital, Hangzhou 310014, China)

机构地区：[1]浙江省人民医院心内科

出　　处：《心电与循环》2019年第3期200-203,共4页Journal of Electrocardiology and Circulation

基　　金：浙江省医药卫生科技计划项目(2018241580)

摘　　要：目的观察急性ST段抬高型心肌梗死(STEMI)发作时间与住院期间恶性心律失常之间的关系。方法回顾性分析212例STEMI患者资料,根据患者不同发病时间将其分为A组(7:00~15:00)84例,B组(15:00~23:00)64例,C组(23:00~7:00)64例,比较3组患者恶性心律失常事件发生率,采用logistic回归方法研究夜间发病的患者发生恶性心律失常事件的相对风险。结果 STEMI发生率最高时段为7:00~8:00,有17例(0.08%),23:00~7:00发病的患者心血管事件发生率最高。3组恶性心律失常的发生率差异有统计学意义(P<0.01),C组明显高于A组、B组(均P<0.05)。logistic回归显示,发病时间与恶性心律失常事件发生率之间存在明显的相关性。结论起病时间在23:00~7:00的STEMI患者院内发生恶性心律失常的风险最高。Objective To study the relationship between the time of ST segment elevation myocardial infarction(STEMI)and malignant arrhythmic events during hospitalization. Methods The data of 212 STEMI patients were analyzed retrospectively. They were divided into Group A(7:00~15:00), Group B(15:00~23:00)and Group C(23:00 ~7:00 next morning)according to onset time of STEMI. The incidences of malignant arrhythmia were compared between groups.Logistic regression was analyzed to evaluate the relative risk of malignant arrhythmia in patients with STEMI occurred during night. Results 17 STEMI occurred during 7:00~8:00. The incidence of cardiovascular events was highest in patients with STEMI occurred during 23:00 PM to 7:00 AM. There was significnatly difference in incidence of malignant arrhythmia among three groups(P<0.01). The incidence was significantly higher in group C than in group A and B(all P<0.05).Conclusion The risk of malignant arrhythmia may increase in patients with STEMI occurring during 23:00 PM and 7:00 AM.

关 键 词：昼夜节律 ST段抬高型心肌梗死 恶性心律失常 

分 类 号：R542.22[医药卫生—心血管疾病]