2型糖尿病患者幽门螺旋杆菌感染情况及胃肠病变特点  

Helicobacter pylori infection and characteristic of gastrointestinal lesions in patients with type 2 diabetes mellitus

作　　者：宋进展 徐光耀[1] 周海燕 李晶晶 SONG Jin-zhan;XU Guang-yao;ZHOU Hai-yan;LI Jing-jing(Endocrinology Department,Beijing Yanqing District Hospital/Peking University Third HospitalYanqing Hospital,Beijing 102100,China;Gastroscopy Room,Beijing Yanqing District Hospital/Peking University Third Hospital Yanqing Hospital,Beijing 102100,China)

机构地区：[1]北京市延庆区医院/北京大学第三医院延庆医院内分泌科,北京102100 [2]北京市延庆区医院/北京大学第三医院延庆医院胃镜室,北京102100

出　　处：《临床医学研究与实践》2019年第14期52-54,共3页Clinical Research and Practice

摘　　要：目的探讨2型糖尿病患者幽门螺旋杆菌感染情况及胃肠病变特点。方法选择行胃镜检查的453患者的病历资料进行回顾性分析,根据是否合并2型糖尿病分为DM组(213例)及NDM组(240例)。观察两组患者幽门螺旋杆菌感染率及胃镜下胃肠病变检出情况,并进一步分析消化性溃疡临床类型、大小及慢性胃炎临床类型。结果 DM组的幽门螺旋杆菌感染率高于NDM组(P<0.05)。DM组消化性溃疡、反流性食管炎及胃肠息肉检出率均高于NDM组(P<0.05);两组十二指肠球炎检出率无显著差异(P>0.05)。DM组的胃溃疡检出率及溃疡直径≥1.0 cm的患者占比高于NDM组(P<0.05);两组十二指肠溃疡及复合型溃疡检出率无显著差异(P>0.05)。两组慢性浅表性胃炎及萎缩性胃炎检出率无显著差异(P>0.05);DM组慢性浅表性胃炎中合并糜烂性胃炎的比例高于NDM组(P<0.05)。结论 2型糖尿病患者幽门螺旋杆菌感染率、消化性溃疡、反流性食管炎、胃肠息肉及糜烂性胃炎检出率高,且胃溃疡占比例高,消化性溃疡面积较大。Objective To investigate the Helicobacter pylori infection and characteristic of gastrointestinal lesionsin in patients with type 2 diabetes mellitus. Methods The data of 453 patients who underwent gastroscopy were retrospectively analyzed, and the patients were divided into DM group(213 cases) and NDM group(240 cases) according to whether had type 2 diabetes mellitus. The infection rate of Helicobacter pylori and the detection of gastrointestinal lesions under gastroscopy of the two groups were observed, the clinical types, size of peptic ulcer and clinical types of chronic gastritis were further analyzed. Results The infection rate of Helicobacter pylori in the DM group was higher than that in the NDM group(P <0.05). The detection rates of peptic ulcer, reflux esophagitis and gastrointestinal polyps in the DM group were higher than those in the NDM group(P<0.05);there was no significant difference in the detection rate of duodenitis between the two groups(P>0.05). The detection rate of gastric ulcer and proprtion of patients with ulcer diameter ≥1.0 cm in the DM group were higher than those in the NDM group(P <0.05);there were no significant differences in detection rates of duodenal ulcer and compound ulcer between the two groups(P>0.05). There were no significant differences in the detection rates of chronic superficial gastritis and atrophic gastritis between the two groups(P >0.05);the proportion of chronic superficial gastritis with erosive gastritis in the DM group was higher than that of the NDM group(P<0.05). Conclusion The Helicobacter pylori infection rate, detection rate of peptic ulcer, reflux esophagitis, gastrointestinal polyps and erosive gastritis in type 2 diabetes mellitus are high, and the proportion of gastric ulcer is high, and the area of peptic ulcer is large.

关 键 词：2 型糖尿病 幽门螺旋杆菌 胃镜 

分 类 号：R587.1[医药卫生—内分泌]