宁波地区52140例患者四项传染病感染特征分析  

Infectious features analysis of four infectious diseases in 52140 cases in Ningbo area

作　　者：孙倩 刘珍 应欣宇 SUN Qian;LIU Zhen;YING Xin-yu(Clinical Laboratory,Ningbo Medical Center Lihuili Eastern Hospital,Ningbo,Zhejiang 315040,China)

机构地区：[1]宁波市医疗中心李惠利东部医院检验科

出　　处：《中国卫生检验杂志》2019年第9期1073-1076,共4页Chinese Journal of Health Laboratory Technology

摘　　要：目的了解宁波地区四项传染病患者特征及重叠感染情况。方法以2015年11月-2018年3月宁波某医院共52140例患者为研究对象,采用ELISA法检测HBsAg、抗TP、抗HCV及抗HIV,将患者按性别、年龄、户籍进行分组,分别统计各组阳性率,并对重叠感染情况进行分析。结果四项指标总阳性率分别为HBsAg(9.41%)、抗TP(3.17%)、抗HCV(0.30%)、抗HIV(0.09%),其中男性患者各项阳性率均明显高于女性(P<0.05);HBV及TP感染率随着年龄增长先上升然后下降,HIV感染趋于低龄化;宁波籍男性抗TP阳性率较高,非宁波籍男性HBsAg、抗HCV及抗HIV阳性率较高(P<0.01);有186例为重叠感染,其中HBV合并TP感染141例,占比最多。结论宁波地区四项传染病以男性群体阳性率较高,尤以中青年为主,同时伴未成年患者增加,宁波籍与非宁波籍患者感染特征不同,中青年男性是防治重点人群;重叠感染较为严重,以HBV合并TP最多。Objective To investigate the characteristics and mixed infection of patients with 4 infectious diseases in Ningbo. Methods A total of 52 140 cases were selected from a hospital for the study from November 2015 to March 2018. HBsAg, Anti-TP, Anti-HCV) and Anti-HIV were detected by ELISA. The patients were divided into groups according to gender, age and household registration. The positive rate of each group was counted and the overlapping infections were analyzed. Results The positive rate of 4 test programs were respectively HBsAg (9. 41 %), Anti-TP ( 3. 17%), Anti-HCV (0. 30%) and Anti-HIV (0. 09%), and the positive rates in males were statistically higher than that in females ( P <0. 05 ). The positive rates of HBsAg, Anti-TP and Anti-HIV were different among age groups (P <0. 05), the infectious rate of TP and HBV gradually increased and then reduced with the growth of age, and HIV infected cases show a lower trend of age. Males with household registered in Ningbo had a higher rate of Anti-TP, on the contrary, a higher rate of HBsAg, HCV and HIV was in males without household registered in Ningbo. And the differences were statistically significant (P <0.01 ). Mixed infection were found in 186 cases, of which 141 cases were with HBV and TP co-infection, accounting for the highest. Conclusion The positive rate of 4 infectious diseases were high in males, predominantly the middle-aged in Ningbo area. The number of minors increased, the infectious characteristics was different between cases with or without household registered in Ningbo, the prevention and control should be focused on the mid-aged males. Mixed infection was serious and most cases were HBV and TP co-infection.

关 键 词：传染性疾病 分布特征 重叠感染 

分 类 号：R181.3[医药卫生—流行病学]