循经取穴合血府逐瘀汤对瘀血阻络型胸痹心痛患者的临床疗效观察  

Clinical Curative Effect of Acupuncture with Acupoint Selection along Meridians Combined with Xuefu Zhuyu Decoction in Treating Chest Stuffiness and Pains of Blood Stasis

作　　者：孙宏[1] 刘凯[2] 蔡国锋[2] 尚莉莉[3] 全爱君 李冀[1] SUN Hong;LIU Kai;CAI Guofeng;SHANG Lili;QUAN Aijun;LI Ji(Heilongjiang University of Chinese Medicine, Harbin 150040, China;The Second Affiliated Hospital ofHeilongjiang University of Chinese Medicine, Harbin 150001, China;Southern Branch, The SecondAffiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150060, China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]黑龙江中医药大学附属第二医院,黑龙江哈尔滨150001 [3]黑龙江中医药大学附属第二医院哈南分院,黑龙江哈尔滨150060

出　　处：《中医药信息》2019年第3期103-106,共4页Information on Traditional Chinese Medicine

基　　金：黑龙江省自然科学基金项目(No.H2018066)

摘　　要：目的:观察循经取穴合血府逐瘀汤治疗瘀血阻络型胸痹心痛患者的临床疗效。方法:将符合纳入标准的60例瘀血痹阻型胸痹心痛患者随机分为对照组、血府逐瘀汤组和针刺协同组,每组20例。对照组给予常规西医治疗,血府逐瘀汤组在对照组治疗的基础上口服血府逐瘀汤,针刺协同组在血府逐瘀汤组基础上给予针刺治疗,比较治疗后各组间的疗效、24 h动态心电图、西雅图心绞痛量表,及cTnI、cTnT、BNP变化情况。结果:治疗后Holter显示,心肌缺血频率、心肌缺血时间及缺血总负荷方面比较,针刺协同组较血府逐瘀汤组和对照组具有统计学差异(P<0.05)。SAQ量表显示,躯体受限程度、心绞痛稳定状态,心绞痛发作情况,针刺协同组及血府逐瘀汤组较对照组比较均有统计学差异(P<0.01)。cTnI、cTnT、BNP变化情况针刺协同组与血府逐瘀汤组治疗后比较无统计学差异(P>0.05)。结论:循经取穴合血府逐瘀汤治疗瘀血阻络型胸痹心痛优于常规西医治疗,能明显改善心功能,提高患者生存质量。Objective: To observe the clinical curative effect of acupuncture with acupoint selection along meridians combined with Xuefu Zhuyu Decoction in treating chest stuffiness and pains of blood stasis. Methods: 60 patients met the inclusion criteria were randomly divided into the control group(routine western medication, n =20), Xuefu Zhuyu Decoction group(routine western medication+Xuefu Zhuyu Decoction, n =20 ) and the combination group(routine western medication+Xuefu Zhuyu Decoction+Acupuncture, n =20). After the treatment, the curative effect, results of 24-hour Holter monitoring, scores of Seattle angina scale, and the changes of cTnI, cTnT and BNP were compared among the groups. Results: The results of 24- hour Holter monitoring showed that there were statistical differences in the frequency of myocardial ischemia, the time of myocardial ischemia and the total load of ischemia between the combination group and the other two groups after the treatment( P <0.05). SAQ scale showed that the physical limitation, stable state of angina pectoris and attack of angina pectoris were signficantly improved in the combination group and in Xuefu Zhuyu Decoction group compared to the control group( P <0.01). There were no statistical differences in the changes of cTnI, cTnT and BNP between the combination group and Xuefu Zhuyu Decoction group( P >0.05). Conclusion: The clinical effect of combined therapy of Xuefu Zhuyu Decoction and acupuncture with acupoint selection along meridians is superior to routine western medication in the treatment of chest stuffiness and pains of blood stasis. It can significantly improve cardiac function and improve life quality of the patients.

关 键 词：胸痹心痛 血府逐瘀汤 循经取穴 心绞痛 

分 类 号：R256.22[医药卫生—中医内科学]