折叠式人工玻璃体球囊的研究进展  

Research progress of foldable capsular vitreous body

作　　者：林舒曼 李金瑛[1] Lin Shuman;Li Jinying(Derpartment of Ophthalmology,Peking University Shenzhen Hospital,Shenzhen 518035,Guangdong,China)

机构地区：[1]北京大学深圳医院眼科,广东深圳518035

出　　处：《国际眼科纵览》2019年第2期105-110,共6页International Review of Ophthalmology

摘　　要：玻璃体视网膜手术后常常需要玻璃体替代物填充玻璃体腔,寻求理想的玻璃体替代物一直是研究热点。折叠式人工玻璃体球囊是一种新型玻璃体替代物,它模拟玻璃体皮层,有良好的物理及光学性能,生物相容性良好,可长期填充于玻璃体。其内部可填充硅油等其他玻璃体替代物,均匀并全方位地支撑视网膜,有效减少相关并发症和延长其他替代物的存留时间。此外,它还能作为一种药物缓释系统释放各种不同药物。折叠式人工玻璃体球囊拥有良好的应用前景,但也存在易引起并发性白内障等问题,有待进一步研究改进,并观察其长期应用效果。Vitreous substitutes play an important role in supporting vitreous chamber after vitro-retinal surgery. The use of current vitreous substitutes has been limited due to their different issues. So the research for ideal vitreous substitutes is still a hot topic. Foldable capsular vitreous body is a new type of vitreous substitute which simulates vitreous cortex. It can be used for long-term tamponade, with good physical, optical properties and biocompatibility. It can evenly support retina at all directions by filling with other vitreous substitutes, effectively reduce the complications and increase the remaining time of these substitutes. In addition, it can release different drugs as a drug delivery system. Foldable capsular vitreous body has good application prospects. But it also has the problem that it' s easy to cause complicated cataract which need further research and improvement. The observation of long-term effect is also needed.

关 键 词：玻璃体替代物 折叠式人工玻璃体球囊 药物缓释系统 

分 类 号：R318.18[医药卫生—生物医学工程]