血液透析联合杏丁注射液治疗慢性肾衰竭的效果观察及对胃肠激素的影响  

Effect of hemodialysis combined with xingding injection on chronic renal failure and its effect on gastrointestinal hormones

作　　者：陈龙 成家友 周冬梅 王金 CHEN Long;CHEN Jiayou;ZHOU Dongmei;WANG Jin(Department of Nephrology,Yichang Minfu Hospital,Yichang 443000,Hubei,China)

机构地区：[1]宜昌民福医院肾内科

出　　处：《中南医学科学杂志》2019年第3期299-302,共4页Medical Science Journal of Central South China

摘　　要：探讨血液透析联合杏丁注射液治疗慢性肾衰竭(CRF)的效果及对胃肠激素的影响。将150例CRF患者随机均分为观察组和对照组,对照组采用血液透析,观察组采用血液透析联合杏丁注射液治疗。结果显示,观察组的总有效率显著高于对照组(P<0.05)。治疗结束后,观察组肾功能指标(24h尿蛋白、BUN、Scr、CCr)、炎性指标(TNF-α、IL-6、IL-8)、胃肠激素(GAS、Leptin、SS)均显著优于对照组(P<0.05)。且在治疗过程中,两组患者不良反应发生率无统计学差异(P>0.05)。血液透析联合杏丁注射液治疗CRF效果显著,可有效改善患者肾功能。To investigate the effect of hemodialysis combined with Xingding injection on chronic renal failure(CRF)and gastrointestinal hormones.150 patients with CRF admitted to our hospital were randomly divided into observation group and control group,75 cases in each group.The control group was treated with hemodialysis,and the observation group was treated by hemodialysis combined with Xing Ding injection.The results showed that the total effective rate of the observation group was significantly higher than that of the control group(P<0.05).After treatment,the renal function indexes(24 h urinary protein,BUN,Scr,CCr),inflammatory indexes(TNF-a,IL-6,IL-8),gastrointestinal hormones(GAS,Leptin,SS)in the observation group were significantly better than those in the control group(P<0.05).In the course of treatment,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Hemodialysis combined with Xing Ding injection is effective in treating CRF.It can effectively improve renal function in patients.

关 键 词：血液透析 杏丁注射液 慢性肾衰竭 胃肠激素 炎性因子 

分 类 号：R692.5[医药卫生—泌尿科学]