永瓣藤的化学成分研究  

Chemical Constituents from Monimopetalum chinense

作　　者：赵兴增[1] 王相云[1] 印敏[1] 郭生虎[2] 冯煦[1] 徐曙[1] ZHAO Xing-zeng;WANG Xiang-yun;YIN Min;GUO Sheng-hu;FENG Xu;XU Shu(Jiangsu Key Laboratory for the Research and Utilization of Plant Resources,Institute of Botany,Jiangsu Province and Chinese Academy of Sciences,Nanjing 210014,China;Agricultural Biotechnology Center,Ningxia Academy of Agriculture and Forestry Science,Yinehuan 750002,China)

机构地区：[1]江苏省中国科学院植物研究所/江苏省植物资源研究与利用重点实验室,江苏南京210014 [2]宁夏农林科学院农业生物技术研究中心,宁夏银川750002

出　　处：《中药材》2018年第12期2823-2826,共4页Journal of Chinese Medicinal Materials

基　　金：宁夏农林科学院农业科技自主创新专项(对外科技合作专项)(DW-X-2018009);国家自然科学基金青年基金项目(31601683);江苏省自然科学基金青年基金项目(BK20160598).

摘　　要：目的:对永瓣藤Monimopetalum chinense Rehd.的化学成分进行研究。方法:永瓣藤茎叶的85%甲醇提取物采用硅胶柱层析进行分离纯化,根据理化性质及波谱数据鉴定化合物的结构。结果:从中分离得到11个化合物,分别鉴定为:算盘子酮(1)、表儿茶素(2)、邻苯二甲酸二丁酯(3)、算盘子酮醇(4)、卫矛酮(5)、木栓酮(6)、卫矛醇(7)、雷公藤酯甲(8)、雷公藤红素(9)、扁蒴藤素(10)、正二十八烷醇(11)。结论:其中,化合物2～5、7～11为首次从该属植物中分离得到。Objective:To study the chemical constituents from Monimopetalum chinense.Methods:The compounds were isolated and purified by silica gel chromatography column from 85%(volume fraction)methanol extracts of the stems and leaves in Monimopetalum chinense.Their structures were elucidated on the basis of physiochemical characteristics and spectrum analysis.Results:Eleven compounds were identified as glochidone(1),epicatechin(2),dibutyl phthalate(3),glochidonol(4),tingenone(5),friedelin(6),dulcitol(7),wilforlide(8),celastrol(9),pristimerin(10),1-octacosanol(11).Conclusion:Compounds 2 to 5 and 7 to 11 are isolated from this genus for the first time.

关 键 词：永瓣藤 化学成分 三萜 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]