Synthesis, Crystal Structure and Fungicidal Activity of 3-(Difluoromethyl)-1-methyl-N-((2-(trifluoromethyl)phenyl) carbamoyl)-1H-pyrazole-4-carboxamide  

作　　者：SUN Na-Bo ZHAI Zhi-Wen TONG Jian-Ying CAI Peng-Peng HE Fang-Yue HAN Liang LIU Xing-Hai 孙娜波;翟志文;童建颖;蔡彭鹏;何方岳;韩亮;刘幸海(College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, China;College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China)

机构地区：[1]College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, China [2]College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China

出　　处：《Chinese Journal of Structural Chemistry》2019年第5期706-712,668,共8页结构化学（英文）

基　　金：funded by the Public Science&Technology Project of Zhejiang Province(No.2017C32011);Mid-Youth Academic Team of Zhejiang Shuren University;Natural Science Foundation of Zhejiang Province(No.LY19C140002)

摘　　要：The title compound 3-（difluoromethyl）-1-methyl-N-（（2-（trifluoromethyl）phenyl）-carbamoyl）-1 H-pyrazole-4-carboxamide(C14 H11 F5 N4 O2) was synthesized, and its structure was confirmed by 1 H NMR, H RMS and X-ray diffraction. It crystallizes in monoclinic system, space group P21/n with a = 6.994（3）, b = 13.860（6）, c = 15.308（7） ?, β = 97.632（6）°, V = 1470.8（11） ?3,Z = 4, the final R = 0.0692 and wR = 0.2108 for 3989 observed reflections with Ⅰ > 2σ（Ⅰ）. The preliminary biological test shows that the title compound has moderate fungicidal activities against Pseudomonas syringae.

关 键 词：PYRAZOLE ACYL urea SYNTHESIS crystal structure FUNGICIDAL activities 

分 类 号：TQ[化学工程]