笋兰化学成分的研究（英文）  

Chemical constituents from Thunia alba

作　　者：陈亚萍 吴荷 李美红 缪敏 赵敏 黄荣[2] 汤祺[3] 李玉鹏 CHEN Ya-ping;WU He;LI Mei-hong;MIAO Min;ZHAO Min;HUANG Rong;TANG Qi;LI Yu-peng(School of Pharmaceutical Science andYunnan Key Laboratory of Pharmacology for Natural Products,Kunming Medical University,Kunming Yunnan 650500;Advanced Analysis and Measurment Center ,Yunnan University,Kunming Yunnan 650091;Dept. of Urology,The 2nd People’s Hospital of YunnanProuince,Kunming Yunnan 650021,China)

机构地区：[1]昆明医科大学药学院暨云南省天然药物药理重点实验室,云南昆明650500 [2]云南大学现代分析测试中心,云南昆明650091 [3]云南省第二人民医院泌尿外科,云南昆明650021

出　　处：《昆明医科大学学报》2019年第6期39-41,共3页Journal of Kunming Medical University

基　　金：supported by grants from the National Natural Science Foundation of China(No.21202066);the Natural Science Foundation of Yunnan Province,China [2017FE468(-025)];the Scientific Research Foundation of Department of Education of Yunnan Province(2015Y151,2016ZDX050)

摘　　要：目的研究笋兰化学成分,发现其活性成分。方法笋兰乙酸乙酯提取、硅胶柱层析和SephadexLH-20柱层析进行分离纯化,波谱分析(核磁共振氢谱、碳谱、和质谱)确定结构。结果从该药用植物花乙酸乙酯萃取部分分离并鉴定了7 个化合物,分别为: stigmasterol (1), batatasin III (2), hircinol (3), scoparone (4),3,5,4'-trihydroxy-3'-methoxy-bibenzyl (5),β-sitosterol (6), 3,7-dihydroxy-2,4-dimethoxyphenanthrene (7)。结论化合物4为首次从本植物中分离得到。Objective To study the chemical constituents from the herbs of Thunia alba and find its bioactive compounds.Methods The compounds were extracted by ethyl acetate and isolated by column chromatography on silica gel and Sephadex LH-20. Their structures were identified by spectroscopic analysis (1H NMR, 13CNMR and EIMS). Results Seven compouds were obtained and identified as stigmasterol (1), batatasin III (2), hircinol (3), scoparone (4), 3,5,4'-trihydroxy-3'-methoxybibenzyl (5),β-sitosterol (6), 3,7-dihydroxy-2,4-dimethoxyphenan- threne (7). Conclusion Compound 4 was isolated from the herbs for the first time.

关 键 词：笋兰 药用植物 化学成分 

分 类 号：R284.2[医药卫生—中药学]