沂南县2007—2017年住院产妇HBsAg检测及新生儿首针乙肝疫苗接种监测结果分析  

Test analysis of inpatient parturient HBsAg and newborns' first vaccinations against hepatitis B in Yinan from 2007 to 2017

作　　者：庄绪香 王如德[2] 高云 李先香 宋晨 ZHUANG Xu-xiang;WANG Ru-de;GAO Yun;LI Xian-xiang;SONG Chen(Center for Disease Control and Prevention of Yinan County,Yinan 276300,China;Linyi City Center for Disease Control and Prevention,Linyi 276003,China)

机构地区：[1]沂南县疾病预防控制中心,山东沂南276300 [2]临沂市疾病预防控制中心,山东临沂276003

出　　处：《泰山医学院学报》2019年第5期351-354,共4页Journal of Taishan Medical College

摘　　要：目的了解沂南县住院分娩产妇乙肝病毒表面抗原(HBsAg)检测、新生儿首针乙肝疫苗接种和母亲HBsAg阳性的新生儿主被动免疫情况,为进一步完善新生儿乙肝免疫预防策略提供参考。方法对沂南县辖区2007—2017年各医院及保健机构产妇HBsAg检测及新生儿乙肝疫苗首针接种情况报表进行汇总分析。结果沂南县2007—2017年住院分娩产妇HBsAg检测率逐年升高,总检测率为96.93%,HBsAg阳性率为0.75%～1.78%,平均阳性率为1.27%。2014—2017年住院产妇HBsAg、HBeAg双阳性在HBsAg阳性人数中平均占比为37.37%。2011—2017年母亲HBsAg阳性的新生儿首针乙肝疫苗接种率为99.92%,HBIG接种率为100%。2007—2017年新生儿首针乙肝疫苗接种率为99.01%,及时接种率为96.49%;本地和非本地新生儿首针乙肝疫苗接种率分别为99.01%和98.98%(P>0.05),及时接种率分别为96.46%和97.42%(P<0.05)。未及时接种的原因为新生儿患病占69.70%,其他原因占13.86%,早产、难产和低出生体重占12.11%,疫苗未供应占1.95%,已接种免疫球蛋白占1.62%,家长拒绝占0.76%。结论沂南县2007—2017年住院分娩产妇HBsAg检测率较高,新生儿首针乙肝疫苗接种率和及时接种率较高; 2007—2017年母亲HBsAg阳性的新生儿主被动免疫接种率较高。Objective:To understand the test result of inpatient parturient HBsAg,newborns' first vaccinations against hepatitis B and passive vaccinations of the newborns whose mothers are HBsAg positive in Yinan.Methods:A meta analysis for the inpatient parturient HBsAg and newborns' first vaccinations against hepatitis B was conducted from various hospitals and medical institutions in Yinan County from 2007 to 2017.Results:The inpatient parturient HBsAg test rate was on the rise and reached 96.93%,HBsAg positive rate was 0.75%~1.78%,and the average positive rate was 1.27%.From 2014 to 2017,the inpatient parturient with HBsAg and HBeAg double positive amounted to 37.37%.From 2011 to 2017,newborns' first vaccinations against hepatitis B rate was 99.01%,and the timely vaccination coverage rate was 96.49%;local and non-local newborns' first vaccinations against hepatitis B rate were 99.01% and 98.98%( P >0.05),and the timely vaccination coverage rate was 96.46% and 97.42%( P <0.05).For those newborns who failed to get the timely vaccination,69.70% was due to diseases,13.86% was due to some other reasons,12.11% was due to premature birth,dystocia and low birth weight,1.95% was due to failure to get the vaccine,1.62% was due to the fact that they had already got immunoglobulin,and 0.76% was due to parents' rejection.Conclusion: There has been a high HBsAg test rate among inpatient parturient in Yinan County from 2007 to 2017,so is the newborns' first vaccination rate against hepatitis B and timely vaccination rate.From 2010 to 2017,the newborns whose mothers are HBsAg positive also have a high rate of active or passive vaccination.

关 键 词：产妇 HBSAG 首针乙肝疫苗 接种 

分 类 号：R181.32[医药卫生—流行病学]