基因组水平的选择信号及其检测方法研究进展  

Research Progress of Genomic Signature of Selection and its Detection Methods

作　　者：王宇占 赵毅强 WANG Yuzhan;ZHAO Yiqiang(College of Biological Sciences,Chinese Academy of Agricultural Sciences,Beijing 100193,China)

机构地区：[1]中国农业大学生物学院

出　　处：《家畜生态学报》2019年第5期1-6,共6页Journal of Domestic Animal Ecology

基　　金：国家自然科学基金(U1704233)

摘　　要：在进化过程中,自然或人工选择在基因组上留下了各种选择信号的印迹。探究不同物种或同一物种不同种群之间的选择信号有助于我们研究物种的进化历史,筛选优势等位基因并应用于遗传育种之中。本文详细介绍了各种经典的选择信号检测方法及其适用场景,并讨论了各自的优缺点和未来的发展方向。During evolution,natural or artificial selection leave extensive selection signatures in the genome.Detecting the selection signatures among species or different populations within same species would help elucidate evolutionary history of species,or screen for dominant alleles for their applications in genetic breeding.In the paper,the classical methods for the detection of selection signatures and their application scenarios were summarized in detail.The advantages and disadvantages of the methods as well as the direction of method developments in future were also discussed.

关 键 词：选择信号 单核苷酸多态性 生物进化 

分 类 号：S811.5[农业科学—畜牧学]