OA-2000与IOLMaster 500、A型超声测量白内障眼部生物学参数的比较  

Comparison of Ocular Biometric Measurement with OA-2000,IOLMaster 500 and A-Scan in Cataract Patients

作　　者：崇晓霞[1] 王岩[1] 王盼 云慧 Xiaoxia Chong;Yan Wang;Pan Wang;Hui Yun(Department of Ophthalmology,Affiliated Hospital of Nei Mongol Medical University,Hohhot 010050,China)

机构地区：[1]内蒙古医科大学附属医院眼科,呼和浩特010050

出　　处：《中华眼视光学与视觉科学杂志》2019年第5期370-374,共5页Chinese Journal Of Optometry Ophthalmology And Visual Science

摘　　要：目的:比较最新的OA-2000光学生物测量仪与广泛应用的IOLMaster500、A型超声测量白内障眼生物学参数的一致性。方法:系列病例研究。选取2018年5-6月内蒙古医科大学附属医院眼科确诊为年龄相关性白内障的患者152例(152眼),对所有患者依次采用OA-2000、IOLMaster500、A型超声波(A超)这3种设备进行检查,获取眼轴长度(AL)、角膜曲率(Ks、Kf)、中央前房深度(ACD)、角膜横径(W-W)、中央角膜厚度(CCT)、晶状体厚度(LT)和人工晶状体(IOL)度数等参数。数据采用方差分析、Pearson相关分析及Bland-Altamn法进行分析。结果:①OA-2000、IOLMaster500、A超对AL和ACD的检出率分别为97.3%、78.2%、100%和99.3%、97.3%、100%;OA-2000、IOLMaster500对Ks/Kf的检出率为99.3%、98.6%;对W-W的检出率为97.3%、94.7%。其中高度近视伴后巩膜葡萄肿且AL≥26mm的17眼中,OA-2000、IOLMaster500、A超对AL的检出率分别为88%(15/17)、65%(11/17)、100%(17/17)。②3种设备间测得的AL、ACD总体差异有统计学意义(F=12.63,P=0.02;F=10.57,P=0.01),其中OA-2000和IOLMaster500测得的AL、ACD参数结果差异无统计学意义,A超与其他2种设备测得的AL、ACD差异均有统计学意义(P<0.001);OA-2000和IOLMaster500测得的Ks/Kf、IOL、W-W参数差异均无统计学意义。③3种设备对AL测量的平均差值:OA-2000和IOLMaster500为0.03mm,OA-2000和A超为0.13mm;3种设备对AL≥26mm的AL测量的平均差值:OA-2000和IOLMaster500为0.06mm,OA-2000和A超为0.43mm。④Pearson相关性分析显示OA-2000和IOLMaster500在AL测量结果中具有较高的相关性(r=0.78,P=0.02)。⑤通过Bland-Altamn法对各设备的AL数据进行一致性分析,结果显示在95%的一致性范围内一致性良好。结论:OA-2000、IOLMaster500、A超在白内障患眼中的眼部生物测量结果无差异,但OA-2000对AL的检出率明显高于IOLMaster500,同时在高度近视伴后巩膜葡萄肿的AL测量中,OA-2000测量的精确性及可靠性更高。Objective:To compare the consistency of OA-2000 with IOLMaster 500 and A-scan for biological measurements.The purpose of this study was to evaluate the measurements of OA-2000 in preoperative examinations of cataract patients.Methods:In this case series study,a total of 152 patients(152 eyes)diagnosed with age-related cataract were selected at the Affiliated Hospital of Nei Mongol Medical University from May to June 2018.All the patients were examined in turn by OA-2000,IOLMaster 500 and A-scan.Measurements by these three instruments were compared for axial length(AL),Ks/Kf,anterior chamber depth(ACD),white-to-white(W-W),lens thickness(LT)and intraocular lens(IOL)dioptor.The results were analyzed by one-way analysis of variance,Pearson correlation and Bland-Altman.Results:①The detection rates of AL and ACD with OA-2000,IOLMaster 500,and A-scan were 97.3%,78.2%,100%,and 99.3%,97.3%,100%,respectively.The detection rates of Ks/Kf with OA-2000 and IOLMaster 500 were 99.3%and 98.6%.The detection rates of W-W with OA-2000 and IOLMaster 500 were 97.3%and 94.7%.Among them,17 eyes had high myopia,posterior scleral grape swelling and an axial length≥26 mm.The detection rates of AL with OA-2000,IOLMaster 500 and A-scan were 88%(15/17),65%(11/17),and 100%(17/17).②There was a significant difference in AL and ACD between the three instruments(F=12.63,P=0.02;F=10.57,P=0.01).The AL,ACD parameters measured by OA-2000 and IOLMaster 500 were not significantly different.There were significant differences in AL and ACD between A-scan and the other two instruments(P<0.001).There were no significant differences in Ks/Kf,IOL or W-W parameters among the three instruments.③The average difference in AL measurements between OA-2000 and IOLmaster 500 was 0.03 mm,between OA-2000 and A-scan was 0.13 mm.The average difference between the three instruments for AL measurements with an axial length≥26 mm:OA-2000 and IOLmaster 500 was 0.06 mm;OA-2000 and A-scan was 0.43 mm.④A Pearson correlation analysis showed that there was a high cor

关 键 词：OA-2000 IOLMASTER 500 A型超声 白内障 眼部生物测量 

分 类 号：R445.1[医药卫生—影像医学与核医学] R776.1[医药卫生—诊断学]