烟草泛素激活酶E1生物信息学分析  

Bioinformatics Analysis of Tobacco Ubiquitin Activating Enzyme E1

作　　者：田熙 薛波[1] 徐成龙[2] 杨彦明[3] 王德勋[4] 户艳霞[4] 苏家恩[4] TIAN Xi;XUE Bo;XU Cheng-long;YANG Yan-ming;WANG De-xun;HU Yan-xia;SU Jia-en(Yangbi County Branch of Dali Prefecture Tobacco Company,Yangbi 672500,China;Xiangyun County Branch of Dali Prefecture Tobacco Company,Xiangyun 672100,China;Eryuan Branch of Dali State Tobacco Company,Eryuan 671200,China;Dali Branch of Yunnan Tobacco Company,Dali 671000,China)

机构地区：[1]大理州烟草公司漾濞县分公司,云南漾濞672500 [2]大理州烟草公司祥云县分公司,云南祥云672100 [3]大理州烟草公司洱源县分公司,云南洱源671200 [4]云南省烟草公司大理州公司,云南大理671000

出　　处：《黑龙江农业科学》2019年第6期1-4,共4页Heilongjiang Agricultural Sciences

基　　金：云南省烟草公司科技项目(2017YN23)

摘　　要：为从生物信息的角度研究烟草泛素激活酶E1,使用Sopma、Swiss model和Meme工具分析烟草泛素激活酶E1序列的二级结构、空间结构和保守基序。结果表明:烟草泛素激活酶E1的各成员中,以NtUAE2的α-螺旋含量最大,空间结构较为稳定;烟草泛素激活酶E1空间结构的主体结构具有3个分支,功能域位于其间,NtUAE1和NtUAE2空间结构模板为6dc6.2.A;NtUAE3的模板为3cmm.2.A;烟草泛素激活酶E1的保守基序中,Motif 3和Motif 4为泛素激活酶的催化半胱氨酸结构域。In order to study the tobacco ubiquitin-activating enzyme E1 from the perspective of biological information,the secondary structure,spatial structure and conserved motif of the tobacco ubiquitin-activating enzyme E1 sequence were analyzed using the Somma,Swiss model and Meme tools.The results showed that among the members of the tobacco ubiquitin-activating enzyme E1,the α-helix content of NtUAE2 was the largest and the spatial structure was stable.The main structure of the tobacco ubiquitin-activating enzyme E1 spatial structure had three branches,and the functional domains were located between them.NtUAE1 and NtUAE2 spatial structure template was 6dc6.2.A;NtUAE3 template was 3cmm.2.A;in the conserved motif of tobacco ubiquitin activating enzyme E1,Motif 3 and Motif 4 are catalytic cytokines of ubiquitin activating enzyme Amino acid domain.

关 键 词：烟草 泛素激活酶E1 生物信息学 

分 类 号：S572[农业科学—烟草工业]