苯基三氟硼酸钾催化的硅烷还原羰基化合物成醇反应  

Potassium Phenyltrifluoroborate-Catalyzed Reduction of Aldehydes and Ketones into Alcohol with Silanes

作　　者：刘建辉[1,2] 王星旸 Liu Jianhui;Wang Xingyang(State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024;School of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin Campus, Panjin 124221)

机构地区：[1]大连理工大学精细化工国家重点实验室,大连116024 [2]大连理工大学盘锦校区石油与化学工程学院,盘锦124221

出　　处：《有机化学》2019年第5期1411-1416,共6页Chinese Journal of Organic Chemistry

基　　金：精细化工国家重点实验室(盘锦)(No.JH2014009);重点大学基础研究基金资助项目~~

摘　　要：研究了以有机硅烷为还原剂选择性还原羰基的反应,在2.5mol% C6H5BF3K,2.2 epuiv.(EtO)3SiH作用下,甲醇为溶剂,室温下将羰基还原为醇.以中等至较高产率得到目标产物.该方法在羰基还原上表现出良好的选择性,为羰基还原提供了一种新的方法.The selective reduction of carbonyl group with organosilane as reducing agent was studied with methanol as a solvent under the action of 2.5 mol% C6H5BF3K and 2.2 epuiv.(EtO)3SiH. The target products were obtained in medium to high yield. This method shows good selectivity and provides a new method for carbonyl reduction.

关 键 词：羰基还原 有机硅烷 苯基三氟硼酸钾 

分 类 号：O621.251[理学—有机化学]