茵陈的药理作用研究进展  

Research progress on pharmacological effect of Artemisiae Scopariae Herba

作　　者：刘玉萍 邱小玉 刘烨 马国[1] LIU Yu-ping;QIU Xiao-yu;LIU Ye;MA Guo(School of Pharmacy,Fudan University,Shanghai 201203,China)

机构地区：[1]复旦大学药学院,上海201203

出　　处：《中草药》2019年第9期2235-2241,共7页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金面上项目(81374051);国家自然科学基金面上项目(81373078);上海市卫生和计划生育委员会科研课题面上项目(201740094);上海市卫生和计划生育委员会中医药科研课题(2018YP001);复旦大学附属闵行医院-复旦大学药学院战略合作融合基金项目(RO-MY201707)

摘　　要：茵陈Artemisiae Scopariae Herba主要化学成分包括香豆素类、黄酮类、有机酸类、挥发油类等。除传统的清热利湿,利胆退黄作用外,茵陈还具有解热、镇痛、抗炎、抗病毒、抗肿瘤、降血压、调血脂、抗骨质疏松、神经保护、调节代谢、预防阿尔茨海默病等多种功效,其药理作用多样,机制复杂。综述茵陈的药理作用及其机制,为茵陈及其制剂的研发和临床应用提供参考。The main chemical components of Artemisiae Scopariae Herba(ASH) include coumarins, flavonoids, organic acids,essential oils, and so on. Except for the traditional actions of clearing and draining dampness-heat, and disinhibiting gallbladder and anti-icteric, ASH has multiple pharmacological activities, such as antipyretic, analgesic, anti-inflammatory, antiviral, antitumor,hypotensive, hypolipidemic, anti-osteoporotic, neuroprotective, metabolic regulation effects, as well as prevention of Alzheimer’s disease, whose mechanism of actions are complex. This article reviews pharmacological actions and the corresponding mechanism of ASH, which can provide reference for the research, development and clinical application of ASH and its preparations.

关 键 词：茵陈 滨蒿 茵陈蒿 保肝 利胆 解热 镇痛 抗炎 抗病毒 抗肿瘤 

分 类 号：R285[医药卫生—中药学]