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作 者:WU Gui-Yun ZHANG Xiao GUO Xue-Ying HUO Lu-Qiong LIU Hong-Xin SHEN Xiao-Ling QIU Sheng-Xiang HU Ying-Jie TAN Hai-Bo
机构地区:[1]Laboratory of Chinese Herbal Drug Discovery, Institute of Tropical Medicine, Guangzhou University of Chinese Medicine [2]Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences [3]Guangdong Institute of Microbiology
出 处:《Chinese Journal of Natural Medicines》2019年第5期381-386,共6页中国天然药物(英文版)
基 金:supported by the National Natural Science Foundation of China(Nos.81773602 and 81502949);the Natural Science Foundation of Guangdong Province(Nos.2016A030313149 and 2016A020217015);the Innovative Team Project of GZUCM(No.2016KYTD04);Pearl River Science and Technology New Star Fund of Guangzhou(No.201605120849569);Guangdong Special Support Program(No.2017TQ04R599);the Foundation of Key Laboratory of Plant Resources Conservation and Sustainable Utilization,South China Botanical Garden,Chinese Academy of Sciences
摘 要:Three new prenylated stilbenes, named as cajanusins A-C(1-3), and one new natural product cajanusin D(4), along with six known derivatives(5-10) were isolated from the leaves of Cajanus cajan. Their structures were fully elucidated by means of extensive spectroscopic methods and comparison with data in the reported literatures. The new compounds of 1 and 2 were evaluated for in vitro cytotoxic activities against a panel of human cancer cell lines.Three new prenylated stilbenes, named as cajanusins A-C(1-3), and one new natural product cajanusin D(4), along with six known derivatives(5-10) were isolated from the leaves of Cajanus cajan. Their structures were fully elucidated by means of extensive spectroscopic methods and comparison with data in the reported literatures. The new compounds of 1 and 2 were evaluated for in vitro cytotoxic activities against a panel of human cancer cell lines.
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