温针灸结合半夏泻心汤治疗糖尿病性胃轻瘫  

Evaluation on therapeutic effect of needle warming moxibustion combined with Banxia-Xiexin decoction in diabetic gastroparesis

作　　者：郭珺[1] 窦进[2] 李然伟[1] Guo Jun;Dou Jin;Li Ranwei(TCM Acupuncture,Beijing University of Traditional Chinese Medicine Affiliated to the National Temple of Traditional Chinese Medicine Hospital,Beijing 100035,China;Internal Medicine of TCM,Beijing University of Traditional Chinese Medicine Affiliated to the National Temple of traditional Chinese Medicine Hospital,Beijing 100035,China)

机构地区：[1]北京中医药大学附属护国寺中医医院针灸科,100035 [2]北京中医药大学附属护国寺中医医院中医内科,100035

出　　处：《国际中医中药杂志》2019年第5期451-453,共3页International Journal of Traditional Chinese Medicine

基　　金：北京市中医药科技项目(JJ2011-51).

摘　　要：目的探讨温针灸结合半夏泻心汤对糖尿病性胃轻瘫(diabetic gastroparesis, DGP)的疗效及对瘦素水平的影响。方法将符合入选标准的86例DGP患者采用随机数字表法分为2组,对照组采用温针灸治疗,观察组在对照组基础上加服半夏泻心汤。2组均治疗4周。采用ELISA法检测血清胃动素、生长抑素和瘦素,评价临床疗效。结果观察组总有效率为97.7%(42/43)、对照组为88.4%(38/43),2组比较差异有统计学意义(χ^2=9.492,P<0.01)。治疗后,观察组血清胃动素[(340.82±51.32)ng/L比(422.42±64.51)ng/L,t=43.184]、瘦素[(1.98±0.24)ng/ml比(2.78±0.27)ng/ml,t=5.330]水平低于对照组(P<0.01),生长抑素[(47.62±7.48)ng/L比(33.26±5.09)ng/L,t=8.494]水平高于对照组(P<0.01)。结论温针灸结合半夏泻心汤可明显缓解DGP患者的临床症状,降低瘦素水平,提高临床疗效。Objective To investigate the effect of warm acupuncture combined with Banxia-Xiexin decoction on diabetic gastroparesis (DGP).Methods A total of 86 DGP patients who met the selected criteria were divided into two groups by random number table method.The control group was treated with warm acupuncture.The observation group added Banxia-Xiexin decoction on the basis of the control group.Both groups were treated for 4 weeks.The clinical efficacy of motilin (MTL),somatostatin (SS) and leptin (LP) were evaluated by ELISA.Results The total effective rate of the observation group was 97.7%(42/43) and the control group was 88.4%(38/43).The difference between the two groups was statistically significant (χ^2=9.492,P<0.01).The post-treatment serum MTL (340.82 ± 51.32 ng/L vs.422.42 ± 64.51 ng/L,t=43.184) and LP (1.98 ± 0.24 ng/ml vs.2.78 ± 0.27 ng/ml,t=5.330) of the observation group were significantly lower than those of the control group (P<0.01),while the serum SS (47.62 ± 7.48 ng/L vs.33.26 ± 5.09 ng/L,t=8.494) was significantly higher than that of the control group (P<0.01).Conclusions The warm acupuncture combined with Banxia-Xiexin decoction can obviously relieve the clinical symptoms of DGP patients,reduce the level of leptin,and there is no obvious adverse reaction.

关 键 词：温针疗法 糖尿病胃轻瘫 半夏泻心汤 瘦素 

分 类 号：R259[医药卫生—中西医结合]