孟鲁司特钠治疗小儿轻中度持续性哮喘分析  

Analysis of treatment of mild and moderate persistent asthma in children by Menglusitena

作　　者：李映林[1] 崔国斌 肖世极 Li Yinglin;Cui Guobin;Xiao Shiji(Pediatrics of Putian College Affiliated Hospital, Putian, Fujian, 351100, China)

机构地区：[1]莆田学院附属医院儿科

出　　处：《当代医学》2019年第18期127-128,共2页Contemporary Medicine

摘　　要：目的分析孟鲁司特钠治疗小儿轻、中度持续性哮喘的疗效。方法选取本院于2015年5月至2016年5月收治了100例轻中度持续哮喘的小儿患者,随机分组,各50例,对照组给予常规治疗,观察组在常规治疗的前提下,给予孟鲁司特钠咀嚼片。治疗前、治疗后3个月测定患儿的心肺功能:FVC、FEV1、FEV1/FVC。并且评估和对比两组的疗效、症状评分。结果①观察组治疗有效率明显高于对照组,数据差异具有统计学意义(P<0.05)。②组内对比,两组患者症状评分治疗后明显比治疗前降低,数据差异具有统计学意义(P<0.05);组间对比,和对照组对比,观察组症状评分治疗后明显比对照组更低,数据差异具有统计学意义(P<0.05)。③组内对比,两组患者治疗后FVC、FEV1水平、FEV1/FVC水平明显比治疗前增加,数据差异具有统计学意义(P<0.05)。结论孟鲁司特钠治疗小儿轻、中度持续性哮喘疗效确切,能够有效的帮助患儿改善其症状与心肺功能,值得应用。Objective To analyze the effect of Menglusitena on mild and moderate persistent asthma in children. Methods From May 2015 to May 2016, 100 children with mild and moderate sustained asthma were admitted to the hospital. They were randomly grouped into 50 cases. The control group was given regular treatment. The observation group was given Menglusite sodium chewing tablets under the premise of regular treatment. The cardiopulmonary function of the child was measured before and 3 months after treatment: FVC, FEV1, FEV1 /FVC. And evaluate and compare the two groups of curative effect, symptom score. Results The effective rate of treatment in the observation group was significantly higher than that in the control group. In the two groups, the difference in symptom score was significantly lower than before treatment (P<0.05). The comparison between the group and the control group showed that the symptom score of the observation group was significantly lower than that of the control group, and the data difference was statistically significant (P<0.05). In 3 groups, FVC, FEV1 level and FEV1/FVC level were significantly higher after treatment than before treatment, and the difference was statistically significant (P<0.05). Conclusion Menglusitena is effective in treating children with mild and moderate persistent asthma, and can effectively help children to improve their symptoms and cardiopulmonary function, which is worthy of application.

关 键 词：孟鲁司特钠 小儿 轻、中度持续性哮喘 心肺功能 

分 类 号：R725.6[医药卫生—儿科]