基于水蒸气蒸馏法提取羌活挥发油的提取动力学考察  

Study on Extraction Kinetic of Volatile Oil from Notopterygium Incisum by Steam Distillation

作　　者：杜鹏 邹俊波[2] 张小飞[2] 史亚军[2] Du Peng;Zou Junbo;Zhang Xiaofei;Shi Yajun(Shaanxi Public Resource Trading Center,Xi'an 712000,China;Shaanxi University of Chinese Medicine)

机构地区：[1]陕西省公共资源交易中心,西安712000 [2]陕西中医药大学

出　　处：《中国药师》2019年第6期1003-1006,共4页China Pharmacist

基　　金：国家自然科学基金项目(编号:81703720);陕西省教育厅2018年度专项科学研究计划(编号:18JK0208、18JS026);陕西省科技厅资助项目(编号:2018SF-314);陕西中医药大学科学研究计划(编号:2017PY29)

摘　　要：目的:利用GC-MS分析,揭示水蒸气蒸馏法提取羌活挥发油的提取动力学规律。方法:利用水蒸气蒸馏法提取羌活挥发油,每30 min收集挥发油提取物,以二十二烷为内标物进行GC-MS相对定量分析,提取主要特征成分,分析其溶出规律。结果:GC-MS共解析挥发性成分144种,(+)-α-蒎烯,3-蒈烯,右旋萜二烯等为主要挥发性成分。3-蒈烯与右旋萜二烯线性相关性明显,但与(+)-α-蒎烯的溶出无明显规律。3-蒈烯尚与(2R-cis)-α,α,4a,8-四甲基的溶出具有一定正相关性,但与其他成分的溶出呈负相关关系。结论:羌活挥发油的提取过程受主要成分3-蒈烯的影响,但具体作用机制有待深入研究。Objective:To reveal the extraction kinetics of the volatile oil from Notopterygium incisum extracted by steam distillation by GC-MS analysis.Methods:The volatile oil of Notopterygium incisum was extracted by steam distillation,and the volatile oil extract was collected every 30 min.GC-MS relative quantitative analysis was carried out with docosane as the internal standard,main characteristic components were extracted and their dissolution rules were analyzed.Results:There were 144 volatile components in the oil including(+)-zep-pinene,3-carene and dexterpene.The linear correlation between 3-carene and dextral terpene was obvious,while no obvious rule was found with the dissolution of(+)-urban-pinene.3-Carene was positively correlated with(2 R-cis)-α,α,4 a,8-tetramethyl,while negatively correlated with the other components.Conclusion:The extraction process of the volatile oil from Notopterygium incisum is affected by the main component 3-carene,while the mechanism needs to be further studied.

关 键 词：水蒸气蒸馏法 羌活 挥发油 动力学考察 

分 类 号：R284.1[医药卫生—中药学]