左西孟旦和米力农治疗慢性心衰急性发作的临床疗效对比分析  

A comparative analysis of the clinical efficacy of levosimendan and milrinone in the treatment of acute episodes of chronic heart failure

作　　者：李志勇 LI Zhi-yong(Second Affiliated Hospital of Harbin Medical University,Heilongjiang Harbin 150086,China)

机构地区：[1]哈尔滨医科大学附属第二医院

出　　处：《临床医药文献电子杂志》2019年第41期5-5,7,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的:分析并对比对慢性心衰急性发作患者使用左西孟旦与米力农治疗的临床疗效。方法:以98例患者作观察对象,选取2017年4月~2018年6月本医院接受救治的慢性心衰急性发作患者中随机抽取的,以随机抽签法作为分组的依据,将患者分成实验组(n=49,给予左西孟旦药物)与对照组(n=49,给予米力农药物)。观察两组患者治疗后的临床指标,记录后作对比。结果:实验组患者的左心室射血分数高于对照组患者,每博心输出量、去甲肾上腺素与N末端脑肽钠前体水平均高于对照组,治疗效果理想,差异有统计学意义(P<0.05)。结论:对慢性心衰急性发作患者使用左西孟旦药物治疗的临床疗效更加显著,患者的各项临床指标均得到显著改善,值得借鉴并将其推广。Objective To analyze and compare the clinical efficacy of levosimendan and milrinone in the treatment of acute attack of chronic heart failure. Methods 98 patients with acute attack of chronic heart failure were randomly selected from April 2017 to June 2018.The patients were divided into experimental group (n = 49,levosimendan) and control group (n = 49, mili pesticide).The clinical indicators of the two groups after treatment were observed and recorded for comparison. Results The left ventricular ejection fraction of the experimental group was higher than that of the control group.The cardiac output,norepinephrine and N-terminal pro-brain natriuretic peptide levels of the experimental group were higher than those of the control group, and the therapeutic effect was ideal (P<0.05). Conclusion The clinical effect of levosimendan in patients with acute attack of chronic heart failure is more remarkable. The clinical indexes of patients have been significantly improved. It is worth learning and promoting.

关 键 词：左西孟旦 米力农 慢性心衰急性发作 临床指标 

分 类 号：R969.4[医药卫生—药理学]