新型3-吲哚-四取代氧化吲哚的无催化剂合成  

Catalyst-free Synthesis of 3-Indolyl Tetrasubstituted Oxindoles

作　　者：韦启迪 汪军鑫 杨楷模 刘雄利[1] 邓国栋[1] WEI Qi-di;WANG Jun-xin;YANG Kai-mo;LIU Xiong-li;DENG Guo-dong(Guizhou Medicine Edicine Edible Plant Resources Research and Developmant Center, School of pharmacy, Guizhou University, Guiyang 550025, China)

机构地区：[1]贵州大学药学院贵州省药食同源植物资源开发工程技术研究中心

出　　处：《合成化学》2019年第6期424-428,438,共6页Chinese Journal of Synthetic Chemistry

基　　金：贵州省科技项目(黔科合J字[2009]2321号)

摘　　要：以3-氯氧化吲哚为原料,在无催化剂条件下发生SN1反应,合成了18个新型的3-吲哚-四取代氧化吲哚,产率34%~77%,其结构经^1H NMR,^13C NMR和HR-MS(ESI-TOF)表征。Eighteen unreported 3-indolyl tetrasubstituted oxindoles were synthesized via a SN1 reaction under catalyst-free condition using 3-chloroxindoles as materials, with yields of 34%~77%. The structures were characterized by ^1H NMR, ^13C NMR and HR-MS(ESI-TOF).

关 键 词：3-氯氧化吲哚 SN1反应 3-吲哚-四取代氧化吲哚 合成 

分 类 号：O626.13[理学—有机化学] O623.7[理学—化学]