优生优育检查中TORCH抗体检测的临床意义  

Clinical significance analysis of TORCH antibody detection in prenatal and postnatal care examination

作　　者：徐翠香[1] 靳占奎[2] 张丽洁[3] 杨江存[4] 沈鑫[5] XU Cuixiang;JIN Zhankui;ZHANG Lijie;YANG Jiangcun;SHEN Xin(Center of Shaanxi Provincial Clinical Laboratory;Department of Orthopaedics;Hematology Research Laboratory;Department of Blood Transfusion;Department of Obstetricsand Gynecology,Shaanxi Provincial People′s Hospital,Xi′an,Shaanxi 710068,China)

机构地区：[1]陕西省人民医院陕西省临床检验中心,西安710068 [2]陕西省人民医院骨科病院,西安710068 [3]陕西省人民医院血液病研究实验室,西安710068 [4]陕西省人民医院输血科,西安710068 [5]陕西省人民医院妇产病院,西安710068

出　　处：《检验医学与临床》2019年第12期1650-1652,共3页Laboratory Medicine and Clinic

基　　金：国家自然科学基金项目(81801647);陕西省科技成果转移与推广计划-获奖成果转化项目(2019CGHJ-09);陕西省人民医院院内孵化基金项目(2015025)

摘　　要：目的 探讨优生优育检查中TORCH抗体检测的临床意义。方法 选取2017年4月至2018年2月该院收治的不孕女性150例纳入观察组,另选取同期进行优生优育检查的女性150例纳入对照组,通过酶联免疫吸附试验检测两组女性血清中TORCH抗体。结果 观察组女性巨细胞病毒-IgM抗体阳性率与单纯疱疹病毒-IgM抗体阳性率高于对照组,差异有统计学意义(P<0.05);观察组女性TORCH-IgG抗体阳性率与对照组比较,差异无统计学意义(P>0.05);观察组TORCH-IgM抗体阳性合并TORCH-IgG抗体阴性发生率明显高于对照组,差异有统计学意义(P<0.05)。结论 TORCH感染检测在促进优生优育方面具有较大的社会意义及重要的流行病学价值。Objective To explore the clinical significance of TORCH antibody detection in prenatal and postnatal care examination. Methods A total of 150 women with infertility in our hospital from April 2017 to February 2018 were selected,and another 150 women in the same period for prenatal and postnatal care examination were selected as control group.The enzyme-linked immunosorbent assay (ELISA) was used to detect the TORCH-specific antibodies in serum in the two groups. Results The positive rate of CMV-IgM and the positive rate of HSV-IgM in observation group were significantly higher than those in control group ( P < 0.05 ).There was no statistically significant difference in the positive rate of TORCH-IgG antibody compared with that in control group ( P >0.05).The incidence rate of positive TORCH-IgM antibody with negative TORCH-IgG antibody in observation group was significantly higher than that in control group ( P < 0.05 ). Conclusion The detection of TORCH infection in prenatal and postnatal care examination has great social significance and important epidemiological value from the respective of prenatal and postnatal care.

关 键 词：TORCH抗体 优生优育 不孕症 

分 类 号：R446.6[医药卫生—诊断学]