女性生殖道衣原体感染患者血清IL-2、IL-6及抗衣原体免疫优势蛋白抗体水平  

Serum levels of IL-2,IL-6 and anti-chlamydia immunodominant protein antibody in women with genital chlamydia infection

作　　者：王优良[1] WANG Youliang(Department of Laboratory Medicine,Daqing Longnan Hospital, Daqing 163453, CHINA)

机构地区：[1]大庆龙南医院检验科

出　　处：《江苏医药》2019年第5期502-504,共3页Jiangsu Medical Journal

摘　　要：目的分析女性生殖道衣原体感染患者血清IL-2、IL-6、抗衣原体免疫优势蛋白抗体水平。方法检测50例女性生殖道衣原体感染患者(观察组)和50例女性健康体检者(对照组)血清IL-2、IL-6和抗衣原体免疫优势蛋白抗体ct841编码蛋白(CT841)、热休克蛋白60(HSP60)、外膜蛋白复合物B蛋白C端肽(OmcBc)和衣原体质粒编码蛋白3(Pgp3)抗体水平。结果观察组血清IL-2和IL-6水平为(4.42±0.73)ng/ml和(163.89±25.37) pg/ml,高于对照组的(3.89±0.52) ng/ml和(147.53±22.30) pg/ml(P<0.05)。观察组CT841、HSP60、OmcBc和Pgp3抗体阳性检出率均高于对照组(P<0.05)。结论女性生殖道衣原体感染患者血清IL-2、IL-6水平及抗衣原体免疫优势蛋白抗体检出率较高,可用于临床辅助诊断。Objective To analyze serum levels of IL-2,IL-6 and anti-chlamydia immunodominant protein antibody in the women with genital chlamydia infection.Methods Serum levels of IL-2,IL-6 and anti-chlamydia immunodominant protein antibody were detected in 50 women with genital chlamydia infection(group A) and 50 healthy women(group B).Results Serum levels of IL-2 and IL-6 in group A were higher than those in group B [(4.42±0.73) ng/ml vs.(3.89±0.52) ng/ml and(163.89±25.37) pg/ml vs.(147.53±22.30) pg/ml](P<0.05).The positive rates of CT841,HSP60,OmcBc and Pgp3 antibody were higher in group A than those in group B(P<0.05).Conclusion Serum levels of IL-2,IL-6 and anti-chlamydia immunodominant protein antibody are higher in the women with genital chlamydia infection,which may be taken as the indicators for clinical assistant diagnosis.

关 键 词：衣原体感染 白细胞介素 抗衣原体免疫优势蛋白抗体 生殖道 

分 类 号：R691[医药卫生—泌尿科学]