23350例输血前患者4项感染性标志物检测结果分析  

Analysis of the detection results of 4 infectious markers in 23350 patients

作　　者：黄滔 刘雨欣 何霞[1] 陈涛 杜晓瑜[1] 唐志伟 HUANG Tao;LIU Yu-xin;HE Xia(Ya'an People's Hospital, Sichuan Ya'an 625000)

机构地区：[1]雅安市人民医院检验科,四川雅安625000 [2]雅安职业技术学院药学检验系,四川雅安625000

出　　处：《医学检验与临床》2019年第4期28-31,共4页Medical Laboratory Science and Clinics

摘　　要：目的:分析四川雅安地区输血前患者人类免疫缺陷病毒(HIV)、梅毒(TP)、丙型肝炎病毒(HCV)、乙型肝炎表面抗原(HBsAg)的感染情况。方法:对2016年10月-2017年11月拟输血的23350例患者进行抗-HIV1/2,抗-TP、抗-HCV和HBsAg检测,根据性别和年龄分组讨论;结果:23350例患者抗-HIV1/2初筛阳性率0.42%、抗-HCV阳性率0.55%、抗-TP阳性率2.05%、HBsAg阳性率5.59%,男性阳性率均高于女性阳性率,其中HIV和HBV感染患者性别的差异具有统计学意义(P<0.05)。4项感染性标志物均以<15实车龄段阳性率最低,抗-HCV以30-44岁年龄段阳性率最高,抗-HIV1/2和HBsAg以45~59岁年龄段阳性皋最高,抗-TP则以≥60岁年龄段阳性率最高。感染科各感染性标志物阳性率均为全院最高,与全院平均水平的差异均具有统计学意义(P<0.05)。结论:雅安地区拟输血患者HIV和TP感染率高于其他地区,HCV感染率高于全国流行率,而HBV感染率低于一般人群;HIV和HBV感染与性别和年龄均密切相关,HCV和TP感染与年龄相关,与性别无关。Objective: To analyze the infection of human immunodeficiency virus (HIV), syphilis (TP), hepatitis C-virus (HCV) and hepatitis B surface antigen (HBsAg) in pre-transfusion patients in Ya'an area of Sichuan. Methods: A total of 23350 patients who were transfused from October 2016 to November 2017 were tested for anti-HIV1/2, anti-TP, anti-HCV and HBsAg, and were grouped according to gender and age. Results: 23350 patients with anti-HIV1/2 initial screening positive rate 0.42%, anti-HCV positive rate 0.55%, anti-TP positive rate 2.05%, HBsAg positive rate 5.59%, male positive rate is higher than female positive rate, and gender difierence of HIV and HBV infection patients Statistically significant (P<0.05). The four positive markers were the lowest in the <15-year age group, the anti-HCV was the highest in the 30-44 age group, and the anti-HIV1/2 and HBsAg were the liighest in the 45-59 age group.-TP has the highest positive rate in the age group M60 years old. The positive rate of infectious markers in the infection department was the highest in the whole hospital, and the difference with the average level of the hospital was statistically significant (P<0.05). Conclusion: The HIV and TP infection rates of patients with blood transfusion in Ya'an area are higher than other areas. The HCV infection rate is higher than the national prevalence rate, and the HBV infection rate is lower than the general population. HIV and HBV infection are closely related to gender and age. For HCV and TP infection, age is closely related but gender is independent.

关 键 词：感染性标志物 人类免疫缺陷病毒 乙型肝炎表面抗原 输血 

分 类 号：R446.6[医药卫生—诊断学]