SPECT双探头前、后位显像分别测量腮腺功能的比较研究  

An investigation of dual-detector SPECT measuring the function of parotid glands by anterior or posterior scanning

作　　者：曾昱 李亚明[1] 李雪娜[1] 刘晓峰[1] 杜补林[1] 李德顺[1] ZENG Yu;LI Ya-ming;LI Xue-na;LIU Xiao-feng;DU Bu-lin;LI De-shun(Department of Nuclear Medicine,the First Hospital of China Medical University,Shenyang 110001,China)

机构地区：[1]中国医科大学附属第一医院核医学科

出　　处：《中国临床医学影像杂志》2019年第6期381-385,共5页Journal of China Clinic Medical Imaging

摘　　要：目的:探讨在SPECT唾液腺显像中分别进行前、后位图像采集获得腮腺功能参数的差异。方法:对64例患者应用SPECT进行对向双探头前、后位99TcmO4-唾液腺动态显像(SGS)。勾画腮腺ROI,获得腮腺净计数(Countnet),并计算前、后位腮腺15 min摄取率(UR15)及酸刺激后排泌分数(EF),使用Wilcoxon秩和检验分别比较前后位15 min腮腺净计数(Countnet15)、酸刺激前最大净计数值(Countmax)、腮腺UR15及EF。结果:前、后位图像中,左腮腺Countnet15分别为2.46±1.29、2.92±1.70(Z=-3.42,P=0.01),右侧分别为2.82±1.55、3.06±1.76(Z=-2.25,P=0.03);左侧腮腺酸刺激前Countmax分别为2.79±1.50、3.23±1.87(Z=-3.09,P<0.01),右侧分别为3.20±1.69、3.48±1.92(Z=-2.17,P=0.03)。前、后位图像中左侧UR15分别为(1.71±0.76)%、(2.74±1.38)%(Z=-6.34,P<0.01),右侧分别为(1.97±1.01)%、(2.86±1.45)%(Z=-6.11,P<0.01);左侧EF分别为(74.84±14.81)%、(76.61±15.91)%(Z=-3.92,P<0.01),右侧分别为(71.17±15.34)%、(71.48±14.90)%(Z=-4.68,P<0.01)。双侧腮腺后位Countnet15、酸刺激前Countmax均高于前位,且差异有统计学意义;双侧腮腺前位UR15均高于后位,且差异有统计学意义;双侧腮腺后位EF均低于前位且差异有统计学意义。结论:前、后位采集腮腺动态显像所获得的摄取及排泌参数均有差异,差异是下颌支的骨性衰减所导致。Objective: To investigate the difference of the functional parameters of the parotid glands obtained by the anterior and posterior scanning in SPECT salivary glands scintigraphy(SGS). Methods: Sixty-four patients underwent SGS, which was performed by dual-detector SPECT with 99TcmO4-. The parotid ROI was delineated to obtain the net counts of parotid glands(Countnet). The 15 min uptake ratio(UR15) of the parotid gland, and the excretion fraction(EF) after acid stimulation at the anterior and posterior imaging were calculated. The Wilcoxon rank-sum test was used to compare the difference in the 15 min net counts(Countnet15), the maximum net count before acid stimulation(Countmax) of the parotid glands, the UR15 and EF of the anterior and posterior scanning, respectively. Results: In the anterior and posterior images, the Countnet15 of the left parotid gland were 2.46±1.29 vs. 2.92±1.70(Z=-3.42, P=0.01), and the right ones were 2.82±1.55 vs. 3.06±1.76, respectively(Z=-2.25,P=0.03). The Countmaxof left parotid gland were 2.79±1.50 vs. 3.23±1.87(Z=-3.09, P<0.01), and the right ones were 3.20±1.69 vs. 3.48±1.92(Z=-2.17, P=0.03). The UR15 of the left parotid at the anterior and posterior images were(1.71 ±0.76)% vs.(2.74 ±1.38)%(Z =-6.34, P <0.01), and the right were(1.97 ±1.01)% vs.(2.86 ±1.45)%(Z =-6.11, P <0.01). The EF of the left parotid were(74.84±14.81)% vs.(76.61 ±15.91)%(Z =-3.92, P <0.01), and the right were(71.17 ±15.34)% vs.(71.48 ±14.90)%(Z=-4.68, P<0.01). The Countnet15 and Countmaxof both parotid glands in the posterior images were significantly higher than the anterior ones. The anterior UR15 of both parotid glands were significantly higher than that in the posterior ones. The EF of both parotids in the posterior images were significantly lower than that in the anterior. Conclusion: There are differences in the uptake and excretion of parotid glands dynamic imaging between the anterior and posterior scanning. The difference is caused by the osseous attenuation of the mandibular branch.

关 键 词：腮腺 体层摄影术 发射型计算机 单光子 体层摄影术 X线计算机 

分 类 号：R333[医药卫生—人体生理学] R817.4[医药卫生—基础医学]