大理州健康人群乙型肝炎表面抗体水平分析  

Analysis of levels of HBsAb among Healthy Human living in Dali

作　　者：何左 徐然 李鸿钧[1] 尤凤凤 Zuo He;Ran Xu;Hongjun Li;Fengfeng You(Dali’s Center for Disease Control and Prevention,Dali,Yunnan 671000,China;Dali People’s Hospital,Yunnan 671000,China)

机构地区：[1]大理州疾病预防控制中心 [2]大理州人民医院,云南大理671000

出　　处：《西藏医药》2019年第3期84-86,共3页Tibetan Medicine

摘　　要：目的了解2016~2018年大理州人群乙型肝炎(乙肝)表面抗体水平(HBsAb),为乙肝防控提供科学依据。方法采集11454份居民血清样本(12个行政区),通过酶联免疫吸附试验(ELISA)法分析HBsA水平情况。结果(1)6231份血清样本检验为阳性(男性2767人,女性3464人),阳性率为31.31%~92.50%,其中:城市达到54.07%,农村达到54.41%(2)HBsAb水平在8至17月齡人群中最高(92.50%),在25至34周岁人群中最低(31.31%)。(3)HBsAb水平与年龄呈负相关(rs=-0.397,P<0.001),与免疫史呈正相关,差异均有统计学意义(P<0.001)。结论本地区居民HBsAb水平较低,应积极推广成人乙肝疫苗接种,以防控乙型肝炎病毒的传播。Objective:To observe the levels of HBsAb among healthy human living in Dali from 2016 to 2018 in order to provide the scientific evidences for preventing and controlling hepatitis B.Methods:In total,11454 serums were collected from 12 regions,and the levels of HBsA was analyzed by enzyme-linked immunosorbent assay(ELISA).Results:(1)Finally,6231 healthy were positive(male 2767,female 3464).The seropositivity was 31.31%~92.50%(urban healthy 54.7%,rural healthy 54.415).(2)The levels of HBsAb achieve the highest rate(92.50%)among 8-17 months of age,and the lowest rate(31.31%)among 25-34 year-olds.(3)There was a negative correlation between HBsAb and age,but found a positive correlation between HBsAb and immunization history.Conclusions:HBsAb levels is low in local residents.Therefore,HBV vaccine inoculating will be actively popularized to prevent and control hepatitis B.

关 键 词：乙型肝炎 表面抗体 防控 

分 类 号：R512.62[医药卫生—内科学]