中药对冠心病的治疗作用及其机制探究  

Study on the Therapeutic Effect and Mechanism of Chinese Materia Medica on Coronary Heart Disease

作　　者：刘金龙 张永和[1] LIU Jinlong;ZHANG Yonghe(Changchun University of Chinese Medicine, Changchun 130117, China)

机构地区：[1]长春中医药大学

出　　处：《长春中医药大学学报》2019年第3期589-592,共4页Journal of Changchun University of Chinese Medicine

基　　金：吉林省科技发展计划项目(201603044YY)

摘　　要：汉代张仲景《金匮要略》中提出"胸痹"。冠心病的发病机制主要包括脂质浸润学说、内皮损伤反应学说、血栓形成和血小板聚集学说。目前在临床上所用到的抗冠心病药物有很多种,各种药物对冠心病的作用机制也不同。中药对冠心病的作用机制主要表现为脂质过氧化、缺血再灌注损伤、钙超载、炎症反应和雌激素等方面。In Han Dynasty Zhang Zhongjing put forward "chest bi" in his JinguiYaolüe. The pathogenesis of coronary heart disease mainly includes lipid infiltration theory, endothelial injury response theory, thrombosis and platelet aggregation theory. At present, there are many kinds of anti-coronary heart disease drugs used in clinic, and the mechanism of action of various drugs on coronary heart disease is also different. The mechanisms of action of Chinese materia medica on coronary heart disease arelipid peroxidation, ischemia reperfusion injury, calcium overload, inflammatory response and estrogen.

关 键 词：中药 冠心病 作用机制 

分 类 号：R285.5[医药卫生—中药学]