基于数据挖掘分析崔学教治疗慢性前列腺炎的用药规律  

Analysis on CUI Xue-jiao’s Medication Rule in Prescriptions for Chronic Prostatitis Based on Data Mining

作　　者：黄杰龙 曾婷婷 潘彩娣 邱云桥[3] 崔学教[3] HUANG Jie-long;ZENG Ting-ting;PAN Cai-ti;QIU Yun-qiao;CUI Xue-jiao(The First Clinical Medical College of Guangzhou University of Chinese Medicine,Guangzhou Guangdong 510405,China;Zhongshan Hospital of Traditional Chinese Medicine,Zhongshan Guangdong 528400,China;The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou Guangdong 510405,China)

机构地区：[1]广州中医药大学第一临床医学院,广东广州510405 [2]中山市中医院,广东中山528400 [3]广州中医药大学第一附属医院,广东广州510405

出　　处：《中医药导报》2019年第9期42-45,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：崔学教全国老中医专家传承工作室(2016年)

摘　　要：目的:分析崔学教教授治疗慢性前列腺炎的用药规律。方法:采集崔学教教授治疗慢性前列腺炎的门诊处方,录入中医传承辅助系统(V2.5),采用该软件集成的数据挖掘方法,分析崔学教教授治疗慢性前列腺炎的用药规律。结果:164首处方共涉及中药109味,使用频次居前8位(频次≥60)的药物分别为泽兰、白芍、延胡索、丹参、金樱子、槐花、莪术、萹蓄,其中泽兰使用频次最高,出现在92首处方中;其次为白芍、延胡索,各出现73次。共提取出“桑椹-覆盆子-菟丝子”“板蓝根-珍珠草-虎杖”“白芍-金樱子-桑螵蛸”等药物核心组合以及“桑椹-覆盆子-菟丝子-金樱子-黄芪-桑螵蛸”“板蓝根-珍珠草-虎杖-柴胡”等演化新处方。结论:崔学教教授治疗慢性前列腺炎多从血瘀、湿热、肝肾亏虚的角度论治,治疗以清热利湿、活血化瘀为大法,佐以补肝益肾、疏肝止痛。Objective: To analyze the experience of professor CUI Xue-jiao in treating chronic prostatitis.Methods: The prescription of professor Cui for the treatment of chronic prostatitis was collected and input into the TCM inheritance assistance system(V2.5). The data mining method integrated with the software was used to analyze the medication rules. Results: A total of 109 herbal medicines were prescribed in 164 prescriptions, and the top 8 drugs(with a frequency of more than 60) were Zelan(herba lycopi), Baishao(radix paeoniae alba),Yanhusuo(corydalis tuber), Danshen(salvia miltiorrhiza), Jinyinzi(fructus rosae laevigatae), Huaihua(flos sophorae), Ezhu(curcuma zedoary) and Bianxu(Polygonum aviculare). Zelan(herba lycopi) was the most frequently used, appearing in 92 prescriptions. Secondly, Baishao(radix paeoniae alba) and Yanhusuo(corydalis tuber), each appear 73 times. We extracted drugs core groups such as "Sanshen(mulberry)-Fupengzi(raspberry)-Tusizi(the seed of chinese dodder)" "Banlangen(isatis root)-Zhenzhucao(common leafflower herb with root)-Huzhan(polygonum cuspidatum)" " Baishao(radix paeoniae alba)-Jinyingzi(fructus rosae laevigatae)-Sanpiaoxiao(mantis eggcase)", as well as evolution of new prescription, including "Sanshen(mulberry)-Fupengzi(raspberry)-Tusizi(the seed of chinese dodder)-Jinyingzi(fructus rosae laevigatae)-Huangqi(Astragalus membranaceus)-Sanpiaoxiao(mantis egg-case" "i Banlangen(isatis root)-Zhenzhucao(common leafflower herb with root)-Huzhan(polygonum cuspidatum)-Chaihu(radix bupleuri)" etc. Conclusion: CUI Xue-jiao treats chronic prostatitis from the perspectives of blood stasis, damp-heat and deficiency of liver and kidney. The treatment is based on clearing away heat and dampness, activating blood circulation and removing blood stasis, supplemented by tonifying liver and kidney, soothing liver and relieving pain.

关 键 词：崔学教 慢性前列腺炎 用药规律 

分 类 号：R277.5[医药卫生—中医学]