持续气道正压通气治疗对阻塞性睡眠呼吸暂停患者心血管事件的预防  

Prevention of cardiovascular events in patients with obstructive sleep apnea by continuous positive airway pressure ventilation

作　　者：樊秀珍[1] Fan Xiuzhen(Department of Respiratory Medicine,Xilin Guole League Hospital,Xilinhot,Inner Mongolia,026000,China)

机构地区：[1]内蒙古锡林郭勒盟医院呼吸内科

出　　处：《当代医学》2019年第19期45-47,共3页Contemporary Medicine

摘　　要：目的探讨持续气道正压通气对阻塞性睡眠呼吸暂停(obstructive sleep apnea syndrome,OSAS)患者心血管事件的预防效果。方法抽取本院2014年1月至2018年2月收治的200例阻塞性睡眠呼吸暂停患者为研究样本,以随机序列软件奇偶数法分为参照组和通气组各100例,参照组采取常规药物对症治疗,通气组在药物治疗的基础上采取持续气道正压通气(continuous positive airway pressure,CPAP)治疗,对比两组患者呼吸指标变化情况、血压水平和心血管事件发生情况。结果通气组LAD、AHI、SBP、DBP水平以及心血管事件发生率均低于参照组,且LSaO2高于参照组,差异具有统计学意义(P<0.05)。结论CPAP能有效改善OSAS患者睡眠呼吸暂停症状,改善通气功能,稳定血压,并可降低患者心血管事件的风险,改善预后质量。Objective To investigate the preventive effect of continuous positive airway pressure(CPAP)on cardiovascular events in patients with obstructive sleep apnea(OSA).Methods 200 patients with obstructive sleep apnea admitted to our hospital from January 2014 to February 2018 were selected as research samples.The patients were divided into control group and ventilation group by random sequence software odd and even number method.The control group received symptomatic treatment with routine drugs.The ventilation group received continuous positive airway pressure ventilation on the basis of drug treatment.The changes of respiratory index and blood of the two groups were compared.Blood pressure level and cardiovascular events.Results The levels of LAD,AHI,SBP,DBP and the incidence of cardiovascular events in ventilation group were lower than those in control group,and LSaO2 was higher than that in control group,the difference was statistically significant(P<0.05).Conclusion CPAP can effectively improve sleep apnea symptoms,ventilation function,blood pressure stabilization,reduce the risk of cardiovascular events and improve the quality of prognosis in OSAS patients.

关 键 词：阻塞性睡眠呼吸暂停 心血管事件 持续气道正压通气 预防效果 

分 类 号：R766[医药卫生—耳鼻咽喉科]