阴道炎与HPV感染及宫颈癌的关系研究  

Relationship between vaginitis,HPV infection and cervical cancer

作　　者：沈媛媛[1] 鲍俊翠[1] 唐金龙[1] 廖亚庭 刘志红[1] 梁轶珩[1] SHEN Yuan Yuan;BAO Jun Cui;TANG Jin Long;LIAO Ya Ting;LIU Zhi Hong;LIANG Yi Heng(Department of Obstetrics and Gynecology,Peking University Shenchen Hospital,Shenchen 518036,China)

机构地区：[1]北京大学深圳医院妇产科

出　　处：《中国妇幼卫生杂志》2019年第3期25-27,共3页Chinese Journal of Women and Children Health

摘　　要：目的探究常见阴道炎和生殖道人乳头瘤病毒(HPV)感染及宫颈癌的关系。方法选择2013年1月-2018年6月北京大学深圳医院就诊的妇女1200例进行回顾性分析,分析比较各种阴道炎患者和正常组的HPV感染率及宫颈癌发生率和不同阴道炎患者之间的HPV感染率及宫颈癌发生率。结果细菌性阴道炎、念珠菌性阴道炎及滴虫性阴道炎的HPV感染率和宫颈癌的发生率显著高于阴道微环境正常者的HPV感染率和宫颈癌发生率。细菌性阴道炎、念珠菌性阴道炎和滴虫性阴道炎三者间的HPV感染率和宫颈癌发生率无差异显著性。结论阴道炎症(细菌性阴道炎、念珠菌性阴道炎和滴虫性阴道炎)与HPV感染有关,其可能通过影响HPV感染间接影响到宫颈癌的发生。Objective To investigate the correlation between common vaginitis and papillomavirus(HPV)infection,cervical cancer.Methods From January 2013 to June 2018,1200 patients of Peking university Shenzhen hospital were selected,and the HPV infection rate and the incidence of cervical cancer between the vaginitis group and the normal group were analyzed.The HPV infection rate and the incidence of cervical cancer between patients with different vaginitis were analyzed.Results The rate of HPV infection and the incidence of cervical cancer in patients with bacterial vaginitis,candida vaginitis and trichomonas vaginitis were significantly higher than those with normal vaginal microenvironment.There was no significant difference in HPV infection rate and incidence of cervical cancer between patients with bacterial vaginitis,candida vaginitis and trichomonas vaginitis.Conclusion Vaginal inflammation including bacterial vaginitis,candida vaginitis and trichomonas vaginitis is associated with HPV infection.Vaginal inflammation may indirectly affects cervical cancer by affecting HPV infection.

关 键 词：阴道炎 HPV感染 宫颈癌 

分 类 号：R711.31[医药卫生—妇产科学]