FGF23在慢性肾脏病中的研究进展  

Research progress in FGF23 in chronic kidney disease

作　　者：蔡明 王兴智[1] CAI Ming;WANG Xingzhi(Department of Nephrology, First Affiliated Hospital of Harbin Medical University, Harbin 150000, China)

机构地区：[1]哈尔滨医科大学附属第一医院肾内科

出　　处：《临床与病理杂志》2019年第6期1327-1330,共4页Journal of Clinical and Pathological Research

基　　金：黑龙江省教育厅海外学人科研资助项目(1253HQ006)~~

摘　　要：慢性肾脏病(chronic kidney disease,CKD)已经成为全球性的健康问题。CKD患者几乎都存在着不同程度的钙磷代谢紊乱、贫血等问题,对患者生活质量和预后造成严重影响。成纤维生长因子(fibroblast growth factor 23,FGF23)是近年来的研究热点,其在骨矿物质代谢、贫血等方面发挥重要调节作用。FGF23可通过多种途径调节血磷,血清FGF23浓度与贫血存在相关性。Chronic kidney disease (CKD) has become a global health problem. CKD patients almost all have different levels of calcium and phosphorus metabolism disorders, anemia and other issues, which have a serious impact on patients' quality of life and prognosis. Fibroblast growth factor 23 (FGF23) is a research hotspot in recent years, which plays an important regulatory role in bone mineral metabolism and anemia. FGF23 can regulate blood phosphorus in a variety of ways, and serum FGF23 concentration is associated with anemia.

关 键 词：慢性肾脏病 成纤维生长因子 促红细胞生成素 贫血 

分 类 号：R692[医药卫生—泌尿科学]