2018年青海省大骨节病历史重病区内、外环境硒及T-2毒素调查分析  

Investigation and analysis of selenium and T-2 toxin in internal and external environment in the historical critical diseased areas of Kaschin-Beck disease in Qinghai Province in 2018

作　　者：马静[1] 张强[1] 喇翠玲[1] 姜泓[1] 陈黎林[1] 白生录[1] 何多龙[1] 李生梅[1] 孟献亚[1] Ma Jing;Zhang Qiang;La Cuiling;Jiang Hong;Cheng Lilin;Bai Shenglu;He Duolong;Li Shengmei;Meng Xianya(Department of Endemic Disease,Institute for Endemic Disease Prevention and Control of Qinghai Province,Xining 811602,China)

机构地区：[1]青海省地方病预防控制所地方病科,西宁811602

出　　处：《中华地方病学杂志》2019年第6期463-466,共4页Chinese Journal of Endemiology

摘　　要：目的了解目前青海省大骨节病历史重病区内、外环境硒及T-2毒素水平。方法2018年在青海省兴海县、贵德县、班玛县3个历史重病区县,分别选择1个病区村和1个非病区村作为调查点,病区村分别为下村、斜马浪村、要什道村,非病区村分别为大米滩村、贡巴村、德昂村。在兴海县、贵德县调查点采集常住6~12周岁儿童发样,检测发硒含量[参考值为(0.60±0.03)mg/kg];在6个调查点,各采集10户家庭的自产主粮样,检测粮食硒含量[小麦硒含量参考值为(0.053±0.007)mg/kg],以及T-2毒素含量;6个调查点,各采集10份土壤,测定土壤硒含量[参考值为(0.24±0.03)mg/kg]。结果兴海县病区村和非病区村儿童发硒含量分别为(0.252±0.071)、(0.296±0.087)mg/kg,贵德县为(0.225±0.032)、(0.238±0.040)mg/kg。兴海县、贵德县、班玛县的病区村和非病区小麦硒含量中位数分别为0.000 19、0.003 66,0.000 15、0.004 16,0.016 78、0.016 94 mg/kg。兴海县、贵德县、班玛县的病区村和非病区土壤硒含量分别为(0.095±0.015)、(0.114±0.014),(0.082±0.013)、(0.083±0.018),(0.080±0.005)、(0.060±0.013)mg/kg。兴海县、贵德县、班玛县的病区村和非病区小麦中T-2毒素含量分别为(3.173±0.762)、(3.100±0.473),(2.506±0.430)、(3.186±0.451),(2.416±0.619)、(2.879±0.456)μg/kg。结论青海省历史大骨节病重病区村儿童发硒含量均接近发硒正常参考值。病区村土壤硒、居民食用主粮硒含量均偏低;居民户主粮均检出一定量的T-2毒素。Objective To understand the current environmental selenium and T-2 toxin levels in the critically ill areas of Kaschin-Beck disease in Qinghai Province.Methods In three historical villages with serious diseases of Kaschin-Beck disease,Xia,Xiemalang and Yaoshidao were selected;at the same time,three villages from non-diseased areas were selected as control villages including Damitan,Gongba and Deang in 2018.Six villages were used as survey sites.Collected hair samples of children aged 6-12 years old,to measure the hair selenium content in Xinghai and Guide survey sites [children's selenium content reference value was (0.60 ± 0.03) mg/kg].Ten samples of self-produced grain were collected from each survey site,selenium content [wheat selenium content reference value was (0.053 ± 0.007) mg/kg] and T-2 toxin content in grain was detected in the six survey sites.Ten soil samples were collected from each survey sites.Soil selenium content was detected in the six survey sites [soil selenium content reference value was (0.24 ± 0.03) mg/kg].Results The selenium contents of children's hair in the diseased and non-diseased areas of Xinghai County,Guide County were (0.252 ± 0.071),(0.296 ± 0.087);(0.225 ± 0.032),(0.238 ± 0.040) mg/kg,respectively.The selenium contents of wheat in the diseased and non-diseased areas of the three counties were 0.000 19,0.003 66;0.000 15,0.004 16;0.016 78,0.016 94 mg/kg.The soil selenium contents in the diseased and non-diseased areas of the three counties were (0.095 ± 0.015),(0.114 ± 0.014);(0.082 ± 0.013),(0.083 ± 0.018);(0.080 ± 0.005),(0.060 ± 0.013) mg/kg.The T-2 toxin contents of wheat in the diseased and non-diseased areas of the three counties were (3.173 ± 0.762),(3.100 ± 0.473);(2.506 ± 0.430),(3.186 ± 0.451);(2.416 ± 0.619),(2.879 ± 0.456)μg/kg.Conclusions The content of hair selenium of children is close to the normal reference value in the area of Kaschin-Beck disease in Qinghai Province.The contents of soil selenium and the main grain selenium of the residents

关 键 词：大骨节病 硒 头发 土壤 T-2毒素 

分 类 号：R684.1[医药卫生—骨科学]