探讨坦洛新在输尿管结石体外冲击波碎石后辅助排石的临床疗效  

To investigate the clinical efficacy of tamsulosin in assisting lithotripsy after extracorporeal shock wave lithotripsy for ureteral calculi

作　　者：苏志宇[1] 郭燕芬[1] 庞健辉[1] Su Zhiyu;Guo Yanfen;Pang JianHui(Zhongshan chenxinghai hospital,528415)

机构地区：[1]中山市陈星海医院药剂科

出　　处：《北方药学》2019年第7期107-108,共2页Journal of North Pharmacy

摘　　要：目的:分析对输尿管结石行体外冲击波碎石后应用坦洛新辅助排石的临床效果。方法:选取80例在我院接受体外冲击波碎石治疗的输尿管结石患者作为临床研究对象,入院时间为2017年2月~2018年2月,以碎石后辅助排石方法的不同分组,实行左氧氟沙星和金甲排石胶囊辅助排石治疗的设为对照组,实行左氧氟沙星、金甲排石胶囊联合坦洛新辅助排石治疗的设为观察组,比对临床疗效。结果:治疗后,观察组一周后以及两周后结石清除率显著高于对照组;观察组二次碎石率显著低于对照组;观察组血尿持续时间、肾绞痛发生率以及镇痛药使用率显著低于对照组,差异均具有统计学意义(P<0.05)。结论:给予输尿管结石行体外冲击波碎石后应用坦洛新辅助排石可提高临床治疗效果,有较高的临床应用价值。Objective: To analyze the clinical effect of tamsulosin in the treatment of ureteral calculi after extracorporeal shock wave lithotripsy (ESWL). Methods: 80 patients with ureteral calculi treated by extracorporeal shock wave lithotripsy were selected as the clinical research object. The admission time was from February 2017 to February 2018. The patients who underwent the treatment of levofloxacin and Jinjiapaishi Capsule as the control group were divided into two groups according to the different methods of assisted lithotripsy after lithotripsy. The patients who underwent the treatment of levofloxacin and Jinjiapaishi Capsule as the assisted litho levofloxacin,Jinjiapaishi Capsule and Tamsulosin Neoadjuvant Lithotripsy were set as observation group,and the clinical efficacy was compared. Result: After treatment,the stone clearance rate in the observation group was significantly higher than that in the control group after one week and two weeks;the second lithotripsy rate in the observation group was significantly lower than that in the control group;the duration of hematuria,the incidence of renal colic and the use rate of analgesics in the observation group were significantly lower than those in the control group,and the difference was uniform. The significance of accounting (P <0.05). Conclusion:The application of tamsulosin in the treatment of ureteral calculi after extracorporeal shock wave lithotripsy can effectively improve the clinical effect and has a high clinical value.

关 键 词：输尿管结石 体外冲击波碎石 坦洛新 辅助排石 临床疗效 

分 类 号：R693.4[医药卫生—泌尿科学]