How cancers usurp macrophages to keep growing  

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作  者:Olmo Sonzogni Gerburg M. Wulf 

机构地区:[1]Beth Israel Deaconess Medical Center, Department of Medicine, Harvard Medical School, Boston, MA 02215, USA

出  处:《Cell Research》2019年第6期423-424,共2页细胞研究(英文版)

摘  要:Liu et al. report the direct interaction of tumor-associated macrophages with cancer stem cells (CSC) through specific ligand-receptor binding (LSECtin-BTN3A3), and how targeting this receptor-ligand interaction decimates the CSC pool. Cancer stem cells (CSC)1 have long been viewed as something akin to primordial matter: at times self-starters able to gen erate an entire tumor when only a few hundred of them are injected, and at other times sleepers that can weather the attack of a chemotherapy treatment only to raise their ugly heads years later.

关 键 词:REPORT cancer CELLS 

分 类 号:Q[生物学]

 

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