1型糖尿病患儿生存质量与糖化血红蛋白的关系分析  

Analysis of the relationship between the quality of life and glycated hemoglobin in children with type 1 diabetes

作　　者：陈龙[1] 李荣[1] 熊丰[1] CHEN Long;LI Rong;XIONG Feng(Department of Endocrinology,Children's hospital of Chongqing Medical University/Ministy of Education Key Laboratory of Child Development and Disorders/China International Science and Technology Cooperation base of Child Development and Critical Disorders/Chongqing Key Laboratory of Pediatrics,Chongqing 400014,China)

机构地区：[1]重庆医科大学附属儿童医院内分泌科/儿童发育疾病研究教育部重点实验室/儿童发育重大疾病国家国际科技合作基地/儿科学重庆市重点实验室

出　　处：《现代医药卫生》2019年第13期1921-1923,1927,共4页Journal of Modern Medicine & Health

基　　金：世界糖尿病基金会(WDF)中国儿童糖尿病管理项目(WDF11-617)

摘　　要：目的评价1型糖尿病儿童的血糖控制情况,探讨1型糖尿病儿童血糖控制情况与其生存质量间的关系。方法采用量表Diabetes Quality of Life for Youths评价2013-2018年度糖尿病夏令营儿童生存质量,现场抽血检查糖化血红蛋白(HbA1c)水平。所有统计分析均使用SAS8.0统计软件。结果93名1型糖尿病儿童中,HbA1c水平达到控制目标者33名,占35.48%,HbA1c水平波动在4.9%~7.9%。1型糖尿病儿童生存质量较低[总分为(75.14±19.35分)],在影响度维度、担忧度维度、满意度维度、自我健康评估方面得分分别为(26.74±7.85)、(23.13±6.60)、(22.60±6.29)、(2.67±0.86)分。1型糖尿病儿童HbA1c水平与生存质量各维度评分均呈正相关(r影响度=0.72,P<0.0001;r担忧度=0.65,P<0.0001;r满意度=0.72,P<0.0001;r自我总体健康评分=0.27,P=0.0093)。结论1型糖尿病儿童血糖控制差,生存质量较低。且血糖控制情况越差,生存质量越低。ObjectiveTo evaluate the glycemic control in type 1 diabetic children,and to explore the relationship between glycemic control and quality of life in children with type 1 diabetes.MethodsUsing modified Diabetes Quality of Life for Youths scale to measure the quality of life of children who participated in Diabetes summer camp in 2013-2018,and blood samples were taken on site to check for HbA1c.All statistical analyses were analyzed by SAS8.0 statistical software.ResultsThe people who′s HbA1c be controled in 93 people type 1 diabetic children was 33 people,accounting for 35.48%,HbA1c numerical fluctuation was 4.9%-7.9%.The quality of life of type 1 diabetic children was low(total score:75.14±19.35).The effect in effect scale,worry scale,satisfaction scale,self-evaluation were significantly(scores of 26.74±7.85,23.13±6.60,22.60±6.29,2.67±0.86,respectively).There were positive correlation between HbA1c and subscales of Diabetes Quality of Life of type 1 diabetic children(r effect scale=0.72,P<0.000 1;r wolly scale=0.65,P<0.000 1;r satisfaction scale=0.72,P<0.000 1;r self-evaluation=0.27,P=0.009 3).ConclusionType 1 diabetic children have poor glycemic control,lower quality of life.And the worse the glycemic control control,the lower the quality of life.

关 键 词：1型糖尿病 糖化血红蛋白 生存质量 

分 类 号：R725.8[医药卫生—儿科]