家属参与式教育对2型糖尿病患者代谢指标影响的Meta分析  

Effect of family participatory health education on metabolism in patients with type 2 diabetes: a Meta-analysis

作　　者：蒋燕 刘安诺[1] 章秋[2] 郑红英[2] 孙小红[2] 潘政雯 Yan Jiang;An-nuo Liu;Qiu Zhang;Hong-ying Zheng;Xiao-hong Sun;Zheng-wen Pan(School of Nursing,Anhui Medical University,Hefei,Anhui 230032,China;Department of Endocrinology,the First Affiliated Hospital of Anhui Medical University,Hefei,Anhui 230022,China)

机构地区：[1]安徽医科大学护理学院,安徽合肥230032 [2]安徽医科大学第一附属医院内分泌科,安徽合肥230022

出　　处：《中国现代医学杂志》2019年第13期56-63,共8页China Journal of Modern Medicine

基　　金：2018年安徽省自然科学基金(No:1808085MH277)

摘　　要：目的评价家属参与式教育对2型糖尿病患者代谢指标产生的效应。方法通过计算机检索多个中英文数据库中的相关文献,然后对符合纳入、排除标准的随机对照研究进行评价,最后采用Stata14.0和RevMan5.3两种软件进行分析。结果纳入的随机对照试验共有11篇。相对于对照组的2型糖尿病患者,家属参与式教育组在降低糖化血红蛋白方面,3个月内[WMD=-0.50(95%CI:-0.61,-0.39),P=0.000]、3~6个月[WMD=-0.57(95%CI:-0.69,-0.45),P=0.000],以及6个月以后[WMD=-0.49(95%CI:-0.76,0.21),P=0.000],两组间差异有统计学意义;在降低空腹血糖水平上差异也有统计学意义[WMD=-17.44,(95%CI:-23.01,-11.87),P=0.000];然而在改善体重指数、总胆固醇、甘油三酯、高密度脂蛋白和低密度脂蛋白水平等指标,差异无统计学意义(P>0.05)。结论针对2型糖尿病患者,家属参与式教育有利于长期改善患者的血糖管理情况,而对体重指数和脂质代谢指标的作用效果尚不能得出确定答案,有待临床开展设计合理的、样本量大的随机对照研究进行验证。Objective To evaluate the effect of family participatory education on metabolicsm in patients with type 2 diabetes.Methods Randomized controlled trials that assess the effectiveness of family participatory education in patients with type 2 diabetes were systematically reviewed using multiple electronic databases.Results A total of 11 randomized controlled trials were included.The meta-analysis showed that,compared with control group,family participatory education lowered glycated hemoglobin levels within 3 months[WMD=-0.50,(95%CI:-0.61,-0.39),P<0.001],during 3 to 6 months[WMD=0.57,(95%CI:0.69,0.45),P<0.001),and post 6 months[WMD=-0.49,(95%CI:-0.76,0.21),P<0.001](P<0.05).Further,family participatory education reduced fasting blood glucose levels[WMD=-17.44,(95%CI:-23.01,-11.87),P<0.001]when compared with control group.There was no statistically significant difference in levels of body mass index,total cholesterol,triglycerides,high-density lipoprotein and low-density lipoprotein(P>0.05)between control group and family participatory education group.Conclusions family participatory education helps control blood glucose but exerts no obvious effect on body mass index and lipid metabolism.

关 键 词：糖尿病 2型 健康教育 META分析 

分 类 号：R587.1[医药卫生—内分泌]