椎体结核与椎体恶性肿瘤的氢质子磁共振波谱对比分析  

Comparative study on proton magnetic resonance spectroscopy of tuberculous spondylitis and vertebral malignant tumors

作　　者：刘斌 郭静 董国礼[2] 黄小华[2] 叶敏[1] LIU Bin;GUO Jing;DONG Guo-li;HUANG Xiao-hua;YE Min(Department of Imaging,The People's Hospital of Chongzhou,Chongzhou 611200;Department of Radiology,Affiliated Hospital of North Sichuan Medicial College,Nanchong 637000,Sichuan,China)

机构地区：[1]崇州市人民医院影像科,四川崇州611200 [2]川北医学院附属医院放射科,四川南充637000

出　　处：《川北医学院学报》2019年第3期359-362,共4页Journal of North Sichuan Medical College

基　　金：四川省卫生厅科研基金(100153)

摘　　要：目的: 应用氢质子磁共振波谱(proton magnetic resonance spectroscopy, 1H-MRS)技术,探讨椎体结核及椎体恶性肿瘤的波谱形态及脂肪含量(FF%),并与各年龄段正常对照组椎体波谱进行对比研究。 方法: 根据纳入及排除标准收集21 例椎体结核患者及19 例椎体恶性肿瘤患者,100 例正常对照按年龄对其进行分组;60 个病变椎体及100 个正常椎体(L2)均行MRI常规序列及 1H-MRS扫描,观察所有椎体的波谱形态,测量并记录FF%值。 结果: 椎体结核组及椎体恶性肿瘤组的波谱形态均表现为水峰高耸、脂肪峰低平或消失,其平均FF%值分别为(7.09±5.43)%及(6.35±7.23)%,两组间比较,差异无统计学意义( P >0.05),但结核组FF%值较肿瘤组稍高;正常对照组各年龄段谱线图可见明显的水峰及脂峰,其FF%值明显高于结核及肿瘤组,差异有统计学意义( P <0.05)。 结论: 椎体结核及恶性肿瘤的谱线形态明显不同于正常椎体,表现为水峰高耸、脂肪峰低平或消失,且病变椎体与正常对照组椎体FF%值间差异具有统计学意义,但与结核组及肿瘤组间差异不具有统计学意义。Objective:To explore the conformation of spectroscopy of tuberculous spondylitis and vertebral malignant tumors,and to investigate their change law of FF% by the way of applying the technique of proton magnetic resonance spectroscopy ( 1H-MRS).And to observe and compare the spectroscopy of lumbar vertebral body 2 of normal control in each age bracket,respectively.Methods:21 cases with tuberculous spondylitis,19 cases with vertebral malignant tumors and 100 cases of normal control were grouped according to age and inclusion and exclusion criteria.All 60 diseased and 100 normal vetebral bodies (L2) were examined with routine magnetic resonance imaging (MRI) sequence and 1H-MRS scanning.All vertebral conformation of spectroscopy was observed and the values of FF% in each group were measured and recorded,respectively.Results:The conformation of spectroscopy of tuberculous spondylitis and vertebral malignant tumors both represented as a very prominent water peak and a low and flat,even disappeared fat peak.The average value of FF% of both groups were (7.09±5.43)% and (6.35±7.23)%,respectively.There was no statistical significance existed in FF% between the two groups ( P >0.05),however,FF% in the groups of tuberculous spondylitis was slightly higher than that in the group of vertebral malignant tumors.The spectroscopeical conformation of lumbar vertebral body 2 of normal control in each age bracket all represented as two very prominent water and fat peak.The statistical analysis indicated that statistical significance respectively existed in FF% between the groups of mormal control and tuberculous spondylitis,and vertebral malignant tumors ( P <0.05).Conclusion:The conformation of spectroscopy of tuberculous spondylitis and vertebral malignant tumors is apparently different from which of the normal control.And the former represented as a very prominent water peak and a low and flat,even disappeared fat peak.The statistical analysis demonstrated that statistically significant difference existed in FF% between the dis

关 键 词：氢质子磁共振波谱 椎体 结核 恶性肿瘤 脂肪含量 

分 类 号：R445.2[医药卫生—影像医学与核医学] R738[医药卫生—诊断学]