腹腔镜联合胆道镜经胆囊管取石治疗胆囊结石合并胆总管结石5年随访效果分析  

Five-year follow-up outcomes of laparoscopic choledochoscopy via the cystic duct for choledocholithiasis in patients with gallstones and common bile duct stones

作　　者：丁国乾 朱杰高[1,2] 汪栋 郭伟[1,2] 张忠涛 Guo-Qian Ding;Jie-Gao Zhu;Dong Wang;Wei Guo;Zhong-Tao Zhang(Department of General Surgery, Beijing Friendship Hospital,Capital Medical University, Beijing 100050, China;National Center for Digestive Disease Research, Beijing 100050, China)

机构地区：[1]首都医科大学附属北京友谊医院普外科,北京市100050 [2]国家消化系统疾病研究中心,北京市100050

出　　处：《世界华人消化杂志》2019年第12期756-760,共5页World Chinese Journal of Digestology

基　　金：国家自然科学基金青年科学基金,No.81603426~~

摘　　要：背景胆囊结石合并胆总管结石的治疗方法有多种,当前较为常用的有腹腔镜下胆囊切除、胆总管探查术,内镜下乳头括约肌切开取石术加腹腔镜胆囊切除术,但前者因术后需放置T管引流、后者因破坏Oddi括约肌而有一定的争议.本研究经胆囊管途径取石,避免了损伤胆总管和Oddi括约肌切开所造成的损伤,在临床中取得了良好的效果.目的探讨腹腔镜下应用胆道镜经胆囊管取石治疗胆囊结石合并胆总管结石的临床效果.方法对2013-01/2013-12的成功实施腹腔镜联合胆道镜经胆囊管取石治疗胆囊结石合并胆总管结石的125例患者进行5年随访,分析其临床治疗效果.结果122例患者成功完成了腹腔镜胆囊切除加联合胆道镜经胆囊管胆总管取石术,手术成功率97.6%,平均年龄58.21岁±13.01岁,手术时间为87.95 min±39.12 min,术中出血11.27 mL±6.85 mL.所有患者均行球囊扩张,其中33例行胆囊管汇合处微切开, 5例行胆道镜下碎石术.患者术后排气时间为32.48 h±17.85 h.术后住院时间为2.03 d±1.62 d.短期随访并发症5.74%,共7例,其中术后胰腺炎4例,经奥曲肽、乌司他丁等对症治疗后治愈,发生胆漏2例,经ENBD引流后治愈,手术切口感染1例,经换药后治愈. 5年远期并发症4.92%,共6例,胆总管复发结石4例,其中1例合并肝内胆管结石,胰腺炎2例.死亡患者4名, 2例心梗, 1例肺部感染, 1例车祸,均与本手术无关.结论腹腔镜联合胆道镜经胆囊管取石治疗胆囊结石合并胆总管结石近期及远期效果较好,患者创伤小,恢复快,并发症少,在临床掌握适应证的前提下,值得推广.BACKGROUND There are many treatments for gallstones combined with common bile duct stones. Currently, laparoscopic cholecystectomy plus common bile duct exploration and endoscopic sphincterotomy plus laparoscopic cholecystectomy are often used, but T tube drainage is required for the former, and the latter is controversial due to the destruction of the Oddi sphincter. AIM To investigate the clinical effect of laparoscopic choledochoscopy in the treatment of gallstones with common bile duct stones. METHODS A total of 125 patients who underwent laparoscopic choledochoscopy and cholecystectomy for gallbladder stones and common bile duct stones were followed for 5 years from January to December 2013. The clinical effects were analyzed. RESULTS The operation was successful in 122 cases, with a success rate of 97.6%. The average age of the patients was 58.21 ± 13.01 years old. The mean operation time was 87.95 ± 39.12 min, and mean intraoperative blood loss was 11.27 ± 6.85 mL. All patients underwent balloon dilatation, of whom 33 underwent microctomy at the confluence of the cystic duct and 5 underwent lithotrity via choledochoscopy. The mean time to first postoperative exhaust was 32.48 ± 17.85 h, and mean postoperative hospital stay was 2.03 ± 1.62 d. The rate of complications at short-term follow-up was 5.74%, and there were a total of 7 cases, including 4 cases of postoperative pancreatitis cured by symptomatic treatment with octreotide and ulinastatin, 2 cases of bile leakage cured by ENBD drainage, and 1 case of surgical wound infection cured by re-dresses. The rate of complications at 5-year follow-up was 4.92%, and there were 4 cases of recurrent common bile duct stones, including 1 case with intrahepatic bile duct stones and 2 cases with pancreatitis. Four patients died, of whom two patients had a myocardial infarction, one had a lung infection, and one had a car accident, all of which were not related to the operation. CONCLUSION Laparoscopic choledochoscopy for the treatment of gallbladder stones combi

关 键 词：腹腔镜 胆道镜 胆囊管 胆囊结石 胆总管结石 

分 类 号：R657.4[医药卫生—外科学]