可见光催化环丙基胺与1,2-二酮衍生物的[3+2]环加成反应  

Visible-Light-Induced [3+2] Annulation of Cyclopropylamines with 1,2-Diketone Derivatives

作　　者：代雪梅 李延军 张少南 龚磊[1] Dai Xuemei;Li Yanjun;Zhang Shaonan;Gong Lei(Key Laboratory of Chemical Biology of Fujian Province,Collaborative Innovation Center of Chemistry for Energy Materials,College of Chemistry and Chemical Engineering,Xiamen University,Xiamen 361005)

机构地区：[1]福建省化学生物学重点实验室能源材料化学协同创新中心厦门大学化学化工学院

出　　处：《有机化学》2019年第6期1711-1719,共9页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.21572184);福建省自然科学基金(No.2017J06006);中央高校基本科研业务费(No.20720160027)资助项目~~

摘　　要：报道了一种可见光催化环丙基胺与1,2-二芳基乙二酮衍生物的[3+2]环加成反应,合成了一系列α-氨基呋喃衍生物,该反应条件温和,产率良好,操作简单.这一方法为潜在生物活性分子骨架α-氨基呋喃衍生物的合成提供了一条高效便捷的路径.A visible-light-induced[3+2]annulation of arylcyclopropylamines and 1,2-diarylethanediones was report.A series ofα-amino tetrahydrofuran derivatives were synthesized in moderate to good isolated yields under mild reaction conditions.This method would provide an efficient and convenient approach toα-amino tetrahydrofurans which are potentially important buiding blocks in bioactive compounds.

关 键 词：光氧化还原 环丙基胺 1 2-二酮衍生物 [3+2]环加成反应 

分 类 号：O621.251[理学—有机化学] O626.11[理学—化学]