二期梅毒误诊为荨麻疹性血管炎1例  

A Case of Secondary Syphilis Misdiagnosed as Urticarial Vasculitis

作　　者：白瑶 石春蕊[1] 刘昱彤 武奕[1] 白瑛[2] 骆志成[2] BAI Yao;SHI Chunrui;LIU Yutong;WU Yi;BAI Ying;LUO Zhicheng(Department of Dermatology,the First Clinical Medicine of Lanzhou University,Lanzhou 730000,China;Department of Dermatology,the Second Clinical Medicine of Lanzhou University,Lanzhou 730000,China)

机构地区：[1]兰州大学第一医院皮肤科,甘肃兰州730000 [2]兰州大学第二医院皮肤科,甘肃兰州730000

出　　处：《中国皮肤性病学杂志》2019年第7期849-850,共2页The Chinese Journal of Dermatovenereology

摘　　要：患者女,20岁,全身出现水肿性红斑伴痒10 d,加重4 d。拟诊“荨麻疹性血管炎”,行梅毒血清学检查:TPPA(+),RPR(+)1:32;皮损组织病理示:角化过度,上皮突存在,棘层肥厚,基底膜完整,真皮浅层及小血管周围可见淋巴细胞及浆细胞浸润。诊断:二期梅毒。给予苄星青霉素240万U驱梅治疗,连用3周。患者皮损已消退,目前在随访中。A 20-year-old female presented with generalized edematous erythema and pruritus for 10 days,which was aggravated for four days.Primary diagnosis was urticarial vasculitis.Syphilis serology revealed TPPA(+)and RPR(+)1:32.Histological examination revealed hyperkeratosis,presence of epidermal ridge,acanthosis,basement membrane intactness,lymphocytes and phlogocytes infiltratration in superficial dermis and perivascular space.The diagnosis of secondary syphilis was made.A dose of 2.4 million U benzathine benzylpenicillin was administered once a week for consecutive three weeks,and the lesions disappeared.Currently,the patient is being followed up.

关 键 词：二期梅毒 荨麻疹性血管炎 误诊 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]