经颈外静脉置管制作SD大鼠CRT模型不同导管固定方法的对比  

Comparison of Different Catheter Fixation Methods for SD Rat CRT Model by External Jugular Vein Catheterization

作　　者：韦艳[1] 甘晓 赵慧函 应燕萍[1] WEI Yan;GAN Xiao;ZHAO Hui-han;YING Yan-ping(Department of Nursing,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi,China)

机构地区：[1]广西医科大学第一附属医院护理部

出　　处：《医学信息》2019年第14期65-67,71,共4页Journal of Medical Information

基　　金：国家自然科学基金(编号:81860032);广西自然科学基金项目(编号:2018G X N SFA A 050081);广西研究生教育创新计划项目(编号:Y CSW 2019115)

摘　　要：目的比较大鼠颈外静脉置管术后两种不同导管固定方法的优缺点。方法将30只清洁级SD大鼠随机分为A、B两组,每组15只。A组:暴露、切开右颈外静脉,置入大鼠颈静脉硅胶导管,导管末端予堵头封管,取适宜长度埋于手术切口皮下,缝合固定。B组:置管、封管方法同A组,将导管从颈背部皮下隧道引出,固定于颈背部。观察两组大鼠术中出血量、手术时长、麻醉药物用量、麻醉苏醒时长及术后7d大鼠导管脱出情况。结果A组术中出血量少于B组[(0.42±0.15)ml vs(1.08±0.31)ml],手术时长短于B组[(30.40±3.48)min vs(46.20±5.16)min],差异有统计学意义(P<0.05);A组10%水合氯醛剂量少于B组[(0.73±0.05)ml vs(0.85±0.11)ml],麻醉苏醒时长短于B组[(52.27±4.06)min vs(61.27±7.36)min],差异有统计学意义(P<0.05)。A组术后7d均无导管脱出,B组术后7d有3只大鼠出现导管脱出。结论将大鼠颈静脉硅胶导管固定于手术切口皮下的方法较将导管经皮下引出,固定于颈背部的固定方法更简便、易行,术中出血量少,手术时间短,麻醉药物用量小,苏醒快。导管埋入皮下,不易脱出,但不利于经静脉导管给药。后者虽有不足,但具有近似模拟临床中心静脉血管通路,还可通过静脉导管给药,进行不同的试验干预等优点。Objective To compare the advantages and disadvantages of two different catheter fixation methods after external jugular vein catheterization in rats.Methods 30 clean SD rats were randomly divided into two groups,A and B,with 15 rats in each group.Group A: Exposure,incision of the right external jugular vein,placement of the rat jugular vein silicone catheter,the end of the catheter was blocked by a plug,and the appropriate length was buried under the skin of the surgical incision and sutured.Group B: The method of catheterization and sealing was the same as that of group A.The catheter was taken out from the subcutaneous tunnel of the neck and back and fixed to the back of the neck.The amount of intraoperative blood loss,duration of surgery,amount of anesthetic drug,length of anesthesia recovery,and catheter eluence at 7 days after surgery were observed.Results The amount of intraoperative blood loss in group A was less than that in group B [(0.42±0.15) ml vs (1.08±0.31) ml],and the length of operation was shorter than that in group B [(30.40±3.48) min vs (46.20±5.16) min],the difference was statistically significant (P<0.05);the dose of 10% chloral hydrate in group A was lower than that in group B [(0.73±0.05) ml vs (0.85±0.11) ml],and the length of anesthesia was shorter than that in group B [(52.27±) 4.06) min vs (61.27±7.36) min],the difference was statistically significant (P<0.05).There was no catheter eruption at 7 d after operation in group A,and catheter degeneration occurred in 3 rats at 7 d after operation.Conclusion The method of fixing the rat jugular vein silicone catheter under the skin of the surgical incision is better than that of the catheter.The fixation method fixed on the neck and back is simpler and easier.The intraoperative blood loss is small,the operation time is short,and the amount of anesthetic is small.Wake up quickly.The catheter is buried under the skin and is not easy to escape,but it is not suitable for intravenous catheter administration.Although the latter is insufficie

关 键 词：颈静脉 置管术 固定 大鼠 

分 类 号：R472[医药卫生—护理学]